Biological Interfaces in Gastrointestinal Cancer 3.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 3625
Special Issue Editors
Interests: liver carcinogenesis; tumor differentiation; chronic liver disease; liver stem cells; tumor stem cells; p53-signalling; aging; telomeres
Special Issues, Collections and Topics in MDPI journals
Interests: CD8 T cells; genetic vaccines; mouse models of chronic HBV infection; development of novel immune therapies against tumors and autoimmune type 1 diabetes; the aging immune system
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are proud to present the third edition of our Special Issue on “Biological Interfaces in Gastrointestinal Cancer”. Our first edition was published in 2020, and since then, we have published over 30 articles in this field.
This Special Issue focuses on the role of communication in gastrointestinal cancers, involving cell-to-cell communication. This includes the communication between the microenvironment or the immune system and the tumor cell as well as the impact of the microbiome. We would love to aso include submissions regarding communication on a molecular level, such as for WNT, RB, p53, NF-κB, and mTOR, which all play major roles in signal transduction.
Gastrointestinal cancers, such as colorectal cancer, pancreatic cancer, and hepatocellular cancer, are associated with a high level of cancer mortality, and thus present a major health problem. Gastrointestinal cancers are characterized by their huge heterogeneity, even if many mutations are present in several tumor entities.
A detailed molecular tumor analysis of biological interfaces is increasingly fundamental in choosing the most appropriate anti-cancer therapy for patients and opening new doors for the development of precision medicine. Interdisciplinary teamwork with colleagues in pathology, bioinformatics, immunology, molecular biology, and other disciplines will help oncologists to integrate data and expertise from the work of professionals involved in prevention, early diagnosis, and basic and translational cancer research.
In this Special Issue, we invite your contributions, either in the form of original research articles, reviews, or shorter perspective articles on all aspects related to the theme of “Biological Interfaces in Gastrointestinal Cancer”.
Dr. Andre Lechel
Prof. Dr. Reinhold Schirmbeck
Guest Editors
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Keywords
- liver cancer
- pancreatic cancer
- intestinal cancer
- gastric cancer
- tissue inflammation
- microenvironment
- innate and adaptive immune responses
- checkpoint inhibitors
- immunotherapy
- precision medicine
- model systems
- transgenic mouse models
- organoid culture
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