Stress Adaptation and Immune Surveillance: Extracellular Vesicles, Autophagy, and Inflammasomes in Cancer and Neurodegeneration
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 20 December 2025 | Viewed by 61
Special Issue Editor
Interests: HIV-1; drug abuse; inflammasomes; neuroinflammation; aging; proinflammatory cytokines; ferroptosis; autophagy; extracellular vesicles
Special Issue Information
Dear Colleagues,
This Special Issue will explore how stress response pathways—including autophagy, ferroptosis, inflammasome activation, and extracellular vesicle (EV) signaling—shape immune surveillance and immune evasion in complex diseases such as cancer, neurodegeneration, and chronic infections. Under conditions of cellular stress, these pathways coordinate survival, cell death, and immune modulation, influencing disease progression and therapeutic outcomes. This Issue aims to highlight mechanistic insights into how these interconnected processes alter the immune landscape within tumor microenvironments and inflamed neural tissues, contributing to immune escape, chronic inflammation, or immunosuppression. We will include original research, reviews, mini-reviews, short communications, and perspectives that address the role of stress-adaptive responses in immune regulation. Topics may include EV-mediated signaling in immune modulation, autophagy-inflammasome crosstalk, stress-induced immune evasion, and novel biomarkers or therapeutic targets.
Dr. Seema Singh
Guest Editor
Manuscript Submission Information
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Keywords
- autophagy
- ferroptosis
- inflammasome activation
- extracellular vesicle (EV)
- cancer
- neurodegeneration
- chronic infections
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