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Cellular and Molecular Mechanisms of CRISPR-Directed Gene Repair
This special issue belongs to the section “Molecular Genetics and Genomics“.
Special Issue Information
Dear Colleagues,
This volume will focus on the mechanisms of gene repair, the molecular reactions that function to repair the double-strand DNA breakage initiated by CRISPR/Cas cleavage of chromosomal or extra -chromosomal DNA. Articles will center on the regulatory circuitry that surrounds genetic engineering in eukarotic cells. We are particularly interested in papers that describe the biochemical and molecular activity responding to the gene editing tools used to modify the genomes of eukaryotic cells, and not the traditional response to external DNA damaging agents.
Dr. Eric Kmiec
Dr. Brett Sansbury
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- CRISPR/Cas
- gene repair
- gene editing
- mechanistic studies
- homology-directed repair
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Published Papers
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