Molecular Insights and Therapeutic Advances in Cerebral and Spinal Tumors
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 January 2026
Special Issue Editor
2. Neurosurgery Department, Sanador Clinical Hospital, 010991 Bucharest, Romania
3. Medical Section, Romanian Academy, 010071 Bucharest, Romania
Interests: neurosurgery; high-grade gliomas; tumoral surgery; pediatric neurosurgery; neuro-oncology; neurosciences; neurovascular pathology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cerebral and spinal tumors represent a complex group of central nervous system (CNS) malignancies with highly heterogeneous molecular profiles and clinical behavior. Despite advances in surgical techniques, radiation therapy, and chemotherapy, outcomes for many patients remain suboptimal due to challenges in diagnosis, therapeutic resistance, and tumor recurrence. This Special Issue aims to highlight recent progress in understanding the molecular and cellular mechanisms underlying CNS tumorigenesis, progression, and response to treatment. We invite original research articles and comprehensive reviews focusing on novel biomarkers, cutting-edge diagnostic methods, genetic and epigenetic alterations, immune modulation, and innovative therapeutic strategies, including targeted therapy, nanotechnology-based delivery, and personalized medicine approaches. By bringing together multidisciplinary insights, we aim to foster a deeper understanding that could lead to improved prognostic tools and more effective treatment paradigms for both cerebral and spinal neoplasms.
Prof. Dr. Alexandru Vladimir Ciurea
Guest Editor
Manuscript Submission Information
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Keywords
- central nervous system tumors
- molecular oncology
- gliomas and spinal cord neoplasms
- targeted therapy and precision medicine
- neuro-oncology biomarkers
- tumor microenvironment
- immunotherapy
- translational neuroscience
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