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Molecular Research on Development and Inhibition of Oral Biofilms

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 11

Special Issue Editor


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Guest Editor
Department of Basic Sciences, Division of Microbiology and Molecular Genetics, Loma Linda University, Loma Linda, CA 92350, USA
Interests: porphyromonas gingivalis; filifactor alocis; bacterial oxidative stress response and virulence regulation; oral biofilms; protein acetylation

Special Issue Information

Dear Colleagues,

Development of oral biofilms leads to most common chronic oral infectious diseases such as dental caries, gingivitis, periodontitis and peri-implantitis. Though our molecular understanding of oral biofilms has been progressed with the recent development of new technologies, these diseases still impose a massive global health care burden, affecting nearly 3.7 billion people worldwide and costing over $710 billion annually. The detailed mechanisms of biofilm formation such as bacterial colonization, interactions between bacterial cell surface adhesins and host receptors as well as chemical communication between bacteria are still not very clear. Given the complexity of oral biofilms, effective management of biofilm-related oral infectious diseases is a global challenge. The focus of this Special Issue is to bring together the recent research works to understand the molecular mechanisms of oral biofilms development and emerging novel innovative strategies to control them.

Suitable topics include, but are not limited to, the following: Molecular mechanisms related to development/maturation of oral biofilms and strategies to inhibit/control dental biofilms such as quorum sensing inhibition, anti-microbial peptides, antibiotics, nanoparticle-based targeting, natural products and new chemicals.

Dr. Arunima Mishra
Guest Editor

Manuscript Submission Information

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Keywords

  • oral biofilms
  • dental plaque
  • biofilm structure/architecture
  • oral biofilm management
  • quorum-sensing inhibitors
  • anti-microbial peptides
  • glucosyltransferases
  • coaggregation

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Published Papers

This special issue is now open for submission.
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