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Pathogenesis and New Treatment in Non-Small Cell Lung Cancer

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".

Deadline for manuscript submissions: 30 October 2025 | Viewed by 26

Special Issue Editor


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Guest Editor
Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy
Interests: biochemistry; oxidative stress; tumorigenesis; cell death pathway; resistance to anticancer therapies
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The leading cause of cancer-related death worldwide is non-small cell lung cancer (NSCLC), which includes adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. It is the most prevalent lung cancer, accounting for around 83% of cases. Due to the common diagnosis of patients in late stages with local invasion or metastasis, chemotherapy and molecular-targeted therapy are frequently employed to improve patient outcomes.

This Special Issue calls for researchers to submit original research and review articles that describe and analyze various aspects of pathogenesis and novel therapeutic approaches in NSCLC. A new understanding of the molecular changes that control signaling pathways and lead to tumorigenesis in NSCLC is welcomed. However, we would like to focus this Special Issue on studies that combine basic and translational research and provide in-depth knowledge of the role of cell death and survival pathways in cancer progression, and the use of innovative therapies. Particular focus will be placed on combined therapies to treat more aggressive and drug-resistant tumors.

Dr. Eleonora Vecchio
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • non-small cell lung cancer
  • drug resistance
  • survival pathway
  • cell death pathway
  • innovative therapies

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Published Papers

This special issue is now open for submission.
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