Advancements in Novel Drug Delivery Systems for Gene and Drug Delivery
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 March 2026 | Viewed by 850
Special Issue Editor
Interests: natural antivirals; host and viruses interaction; intracellular trafficking of viral infection; herpesviruses; HSV-1; viral immune evasion; virus-induced cell death; RNAi; small RNAs as therapeutics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, drug and gene delivery technologies have undergone significant advancements, leading to the development of more precise, efficient, and safer therapeutic strategies. Traditional drug delivery methods often face challenges such as low bioavailability, off-target effects, and rapid systemic clearance. Similarly, gene therapy approaches require innovative carriers to ensure efficient cellular uptake, stability, and targeted delivery. To address these challenges, researchers have increasingly focused on novel delivery platforms, including nanotechnology-based carriers, biomaterial-based systems, and bioengineered vectors. These advancements are particularly relevant for the treatment of complex diseases such as cancer, infectious diseases, and genetic disorders, where targeted and controlled drug and gene release can significantly improve therapeutic outcomes. This Special Issue aims to collect the latest research and innovations in this field, focusing on cutting-edge delivery platforms, biocompatible nanocarriers, and emerging biomaterial-based approaches. We invite researchers to contribute original studies and systematic reviews that explore innovative strategies for enhancing the precision, efficacy, and biocompatibility of drug and gene delivery systems. We encourage submissions of papers covering (1) nanoparticle-based delivery systems such as liposomes, polymeric nanoparticles, dendrimers, and graphene- and lipid-based carriers for drug and gene transport; (2) viral and non-viral gene delivery approaches such as CRISPR/Cas9 systems, siRNA/mRNA therapeutics, and novel vector technologies; and (3) advanced biomaterials such as hydrogels, micelles, and extracellular vesicles for sustained and controlled release.
Dr. Rosamaria Pennisi
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- drug and gene delivery
- novel drug delivery systems
- nanoparticle-based delivery systems
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
