Contemporary Challenges and Problems in Health
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Editors
Prof. Dr. Andrzej M. Śliwczyński
Prof. Dr. Andrzej M. Śliwczyński
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Website
Collection Editor
1. Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Wołoska 137, 02-507 Warszawa, Poland
2. Satellite Campus in Warsaw, University of Humanities and Economics in Lodz, 90-212 Lodz, Poland
Interests: data analysis; health data; data on medical benefits in health; health trend analysis; health costs; availability and health safety; clinical; economic and organizational effectiveness of therapy
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Dr. Izabela Gołębiak
Dr. Izabela Gołębiak
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Website
Collection Editor
Faculty of Medicine, Lazarski University, 02-662 Warszawa, Poland
Interests: vaccinology; epidemiology; public health data analysis; health data; data on medical benefits in health; health trend analysis; health costs; health availability and safety; clinical, economic and organizational effectiveness of therapy
Special Issues, Collections and Topics in MDPI journals
Dr. Zofia Sienkiewicz
Dr. Zofia Sienkiewicz
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Website
Collection Editor
Department of Development of Nursing, Social and Medical Sciences, Faculty of Health Sciences, Medical University of Warsaw, Żwirki i Wigury 61, 02-091 Warsaw, Poland
Interests: health threats connected to the profession of nurse; the process of preparation to perform educational tasks; problems of senior citizens; communication in interdisciplinary teams; nursing theories aimed for use in nursing practice; multicultural nursing; shaping intercultural awareness
Special Issues, Collections and Topics in MDPI journals
Topical Collection Information
Dear Colleagues,
We observe the intensive development of health-supporting science (medicine, pharmacy and health sciences). New therapeutic (not only drug), diagnostic and logistic technologies (supporting medical organizations and the work of medical professionals) are being developed. This progress allows us to respond to new health problems and to better recognize and treat them. We must share discoveries and knowledge, because only in this way will our patients be safer and healthier.
This collection is designed to help communicate important information about diseases, technologies, and observations in all aspects to help heal patients. We want to show that the knowledge of problems and new technological solutions helps and accelerates the development of medicine and health sciences.
Therefore, we welcome all articles, systematic reviews and other original productions that address research topics related to this thematic collection
Manuscripts submitted for publication - in accordance with the requirements of the Editorial Board - will be subject to a review process.
Prof. Dr. Andrzej M. Śliwczyński
Dr. Izabela Gołębiak
Dr. Zofia Sienkiewicz
Collection Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the collection website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- health innovations
- health problems
- innovation in the treatment of patients
- problems in treating patients new solutions and diagnostic problems
- new solutions and therapeutic problems
- new solutions and organizational problems
- new it solutions
- new it applications
Published Papers (4 papers)
Open AccessArticle
A Comparison Study of the Western Ontario Rotator Cuff Index, and the Constant–Murley Score with Objective Assessment of External Rotator Muscle Strength and Pain in Patients after Arthroscopic Rotator Cuff Repair
by
Agnieszka Bejer, Jędrzej Płocki, Mirosław Probachta, Ireneusz Kotela and Andrzej Kotela
Cited by 2 | Viewed by 1612
Abstract
Although rotator cuff injures are often associated with a limited range of motion and muscle weakness, being able to conduct pain-free and efficient performances of the activities as part of daily living seems to be more important for patients. The aim of this
[...] Read more.
Although rotator cuff injures are often associated with a limited range of motion and muscle weakness, being able to conduct pain-free and efficient performances of the activities as part of daily living seems to be more important for patients. The aim of this study was to investigate the correlation between two questionnaires—the disease-specific, subjective questionnaire termed the Western Ontario Rotator Cuff Index (WORC), and the shoulder-specific, subjective-objective questionnaire Constant–Murley score (CMS), with the objective assessment of external rotator muscle strength, and the subjective assessment of pain according to the visual analog scale (VAS) in patients after arthroscopic rotator cuff repair. The study was carried out among 47 patients twice—6 and 12 months after surgery, respectively. All patients completed the WORC, the CMS, and the VAS. Isokinetic evaluation of the external rotators was performed using the Biodex 4 ProSystem. The correlations of all assessed muscle strength parameters with both the CMS and the WORC were found to be statistically significant, being mostly average during the 1st examination and mostly strong during the 2nd examination. There was a significant improvement in all assessed tools as a result of the undertaken rehabilitation. There were weak correlations present between changes in the WORC and changes in the external rotator muscle strength, with correlations between WORC-Sport and EXT90
0-AVERAGE-POWER and PEAK-TORQUE also being found statistically significant. Correlations of changes in the CMS scale with changes in the external rotator muscle strength were weak and statistically insignificant. It seems that the WORC questionnaire can be recommended more for the population after rotator cuff repair, which allows for a reliable assessment of patients’ ability to function and its changes in various areas of life, and at the same time does not require a direct assessment by a clinician or researcher.
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Open AccessArticle
Glutathione S-Transferase P1 Genetic Variant’s Influence on the HbA1c Level in Type Two Diabetic Patients
by
Katarzyna Orlewska, Justyna Klusek, Stanisław Głuszek, Jolanta Klusek, Bartosz Witczak, Monika Wawszczak, Łukasz Madej, Michał Tomasz Marzec and Ewa Orlewska
Cited by 2 | Viewed by 1627
Abstract
GST (glutathione S-transferases) are capable of influencing glucose homeostasis, probably through regulation of the response to oxidant stress. The aim of our study was to investigate the relationship between GSTP1 gene polymorphism and glycated hemoglobin (HbA1c) levels in type two diabetic (T2D) patients.
[...] Read more.
GST (glutathione S-transferases) are capable of influencing glucose homeostasis, probably through regulation of the response to oxidant stress. The aim of our study was to investigate the relationship between GSTP1 gene polymorphism and glycated hemoglobin (HbA1c) levels in type two diabetic (T2D) patients. A total of 307 T2D patients were included. Analysis of the GSTP1 gene polymorphism (rs1695) was conducted using the TaqMan qPCR method endpoint genotyping. HbA1c was determined using a COBAS 6000 autoanalyzer. A univariable linear regression and multivariable linear regression model were used to investigate the association between mean HbA1c level and GSTP1 gene polymorphism, age at T2D diagnosis, T2D duration, therapy with insulin, gender, BMI, smoking status. GSTP1 Val/Val genotype, age at T2D diagnosis, T2D duration and therapy with insulin were statistically significant contributors to HbA1c levels (
p < 0.05). Multivariable regression analysis revealed that GSTP1 (Val/Val vs. Ile/Ile) was associated with higher HbA1c even after adjustment for variables that showed a statistically significant relationship with HbA1c in univariable analyses (
p = 0.024). The results suggest that GSTP polymorphism may be one of the risk factors for higher HbA1c in T2D patients. Our study is limited by the relatively small sample size, cross-sectional design, and lack of inclusion of other oxidative stress-related genetic variants.
Full article
Open AccessArticle
Binge Eating Disorder—The Point Prevalence among Polish Women with Polycystic Ovary Syndrome and Validity of Screening Tool for This Population
by
Katarzyna Suchta, Roman Smolarczyk, Krzysztof Czajkowski, Ewa Rudnicka and Andrzej Kokoszka
Cited by 2 | Viewed by 1777
Abstract
Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders which is associated with an increased risk of metabolic dysregulation. The elevated prevalence of obesity has been observed in women with PCOS. Since obesity is commonly associated with eating disturbances,
[...] Read more.
Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders which is associated with an increased risk of metabolic dysregulation. The elevated prevalence of obesity has been observed in women with PCOS. Since obesity is commonly associated with eating disturbances, including the binge eating disorder (BED), and since the hormonal changes in PCOS patients could influence the food intake model, we decided to estimate the prevalence of BED in PCOS patients and to assess the sensitivity and specificity of the Questionnaire for Binge Eating Screening (QBES) in PCOS patients. Methods: A total of 122 hospitalized women with PCOS aged 16–45 (M = 26; SD = 5.22) took part in the study. Binge eating disorder (BED) was diagnosed according to the DSM-5 diagnostic criteria. QBES was used as a screening tool for BED. Results: The point prevalence of BED in PCOS women according to DMS-5 criteria was 51 (42%). At least two positive answers to four QBES items had 100% sensitivity and 91% specificity. Positive answers to even only the first two questions from QBES had 98% sensitivity and 85% specificity. Conclusions: Women with polycystic ovary syndrome are at a very high risk of binge eating behaviors. Screening for eating disorders should be a routine procedure in women with PCOS. The first two questions from QBES are a brief and relatively reliable screening tool that may be used in everyday practice with POSC patients.
Full article
Open AccessSystematic Review
Does Diabetes Mellitus Increase the Risk of Avascular Osteonecrosis? A Systematic Review and Meta-Analysis
by
Wojciech Konarski, Tomasz Poboży, Andrzej Kotela, Andrzej Śliwczyński, Ireneusz Kotela, Martyna Hordowicz and Jan Krakowiak
Cited by 11 | Viewed by 2494
Abstract
Avascular osteonecrosis (AVN) is caused by the disrupted blood supply to the bone. Most AVN cases occur in the femoral head, but other sites might be affected as well, including the jaw or distal bones of the extremities. Previous studies suggested that diabetes
[...] Read more.
Avascular osteonecrosis (AVN) is caused by the disrupted blood supply to the bone. Most AVN cases occur in the femoral head, but other sites might be affected as well, including the jaw or distal bones of the extremities. Previous studies suggested that diabetes could increase the risk of AVN of the jaw, but the relationship between diabetes and AVN in other bone sites is unclear. This systematic review and meta-analysis aimed to summarize the evidence from studies that had reported on the occurrence of AVN in sites other than the jaw, depending on the diagnosis of diabetes. Overall, we included 6 observational studies carried out in different populations: primary or secondary AVN of the femoral head, Takayasu arteritis, general population, kidney transplant recipients, systemic lupus erythematosus, and primary brain tumors. A random-effects meta-analysis showed that the risk of AVN in sites other than the jaw was non-significantly increased in patients with diabetes (odds ratio: 1.90, 95% confidence interval: 0.93–3.91). The pooled estimate increased and was significant after the exclusion of one study (2.46, 1.14–5.32). There was a significant heterogeneity (I
2 = 65%, tau
2 = 0.48,
p = 0.01; prediction interval, 0.21–16.84). There was no significant publication bias (
p = 0.432). In conclusion, diabetes could increase the risk of AVN in sites other than the jaw, but the available evidence is limited. There is a need for large, well-designed, population-based studies.
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