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Effects of Overuse Injury on Musculoskeletal Tissues

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Global Health".

Deadline for manuscript submissions: closed (15 January 2020) | Viewed by 2887

Special Issue Editor


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Guest Editor
Department of Anatomy and Cell Biology, Temple School of Medicine, 3500 N. Broad Street, Philadelphia, PA 19140, USA
Interests: overuse injuries; repetitive strain injuries; work-related musculoskeletal disorders and injuries

Special Issue Information

Dear Colleagues, 

We are organizing a Special Issue on “Effects of Overuse Injury on Musculoskeletal Tissues” for the International Journal of Environmental Research and Public Health (IJERPH), which is a peer-reviewed scientific journal that publishes articles and communications in the interdisciplinary area of environmental health sciences and public health. More detailed information can be found in https://www.mdpi.com/journal/ijerph.

Overuse injuries are a leading cause of pain and physical disability worldwide and can lead to tendinopathies, myalgia, neuritis, nerve compression syndromes, osteoarthritis, and even osteopenia in involved bones. Several risk factors have been identified, including high repetition, high force, aging, and more, although the interaction of these risk factors needs further investigation, particularly in light of extended retirement times for workers worldwide. There is a continued need for etiologic research examining underlying mechanisms, since effective prevention and treatments are still hampered by many unknowns and problems. For example, there is a continued need for longitudinal studies in young adults to aging humans to understand the effects of changes in repair mechanisms, hormones, metabolism, and inflammation occurring with aging. Further, thresholds for damage need to be defined, as do rest and recovery allowances that would enhance tissue recovery and adaptation.

The submission of prospective studies (e.g., cohort and randomized clinical trials and animal studies) investigating the effects of overuse injury on musculoskeletal tissues (including nerves) and potential treatments is encouraged, although well-designed cross-sectional studies are also welcome. We will also consider comprehensive reviews and/or short communications.

Prof. Mary F. Barbe
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Overuse injuries
  • Repetitive strain injuries
  • Repetitive motion injuries
  • Work-related musculoskeletal disorders/injuries
  • Effective treatments for musculoskeletal disorders
  • Risk Factors for overuse injuries

Published Papers (1 paper)

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Research

12 pages, 1738 KiB  
Article
Plasma MMP-9, TIMP-1, and TGF-β1 Responses to Exercise-Induced Muscle Injury
by Jooyoung Kim and Joohyung Lee
Int. J. Environ. Res. Public Health 2020, 17(2), 566; https://doi.org/10.3390/ijerph17020566 - 16 Jan 2020
Cited by 3 | Viewed by 2605
Abstract
The purpose of this study was to analyze changes in the levels of matrix metalloproteinase-9 (MMP-9), tissue inhibitor of metalloproteinase-1 (TIMP-1), and transforming growth factor-β1 (TGF-β1) in response to strength recovery after eccentric exercise in humans. In this study, 16 healthy males participated [...] Read more.
The purpose of this study was to analyze changes in the levels of matrix metalloproteinase-9 (MMP-9), tissue inhibitor of metalloproteinase-1 (TIMP-1), and transforming growth factor-β1 (TGF-β1) in response to strength recovery after eccentric exercise in humans. In this study, 16 healthy males participated and were divided into a faster recovery (FR) group (n = 8, >80% of baseline) and a slower recovery (SR) group (n = 8, <40% of baseline) on the basis of their recovery of maximal isometric strength (MIS) 96 h after eccentric exercise. For both groups, measurements were taken of muscle soreness, creatine kinase (CK) activity, and MMP-9, TIMP-1, and TGF-β1 levels during the 24- to 96-h period after eccentric muscle contraction of their non-dominant elbow flexor. Muscle soreness (p < 0.001), CK activity (p < 0.01), and TGF-β1 level (p < 0.01) were significantly lower in the FR group compared with SR group, whereas no significant differences in MMP-9 and TIMP-1 levels were found between the two groups (p > 0.05). These results suggest that scar tissue formation caused by the pro-fibrotic activity of growth factors such as TGF-β1 is a potential cause of delay in strength recovery after exercise-induced muscle injury. Full article
(This article belongs to the Special Issue Effects of Overuse Injury on Musculoskeletal Tissues)
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