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Burden of Cancer Worldwide

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Global Health".

Deadline for manuscript submissions: 28 February 2026 | Viewed by 2885

Special Issue Editors


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Guest Editor
Health School, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil
Interests: epidemiology; public policy; social inequalities; cancer mortality and morbidity levels and trends; cancer transition; population-attributable fractions (PAF) for a combination of cancer risk

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Guest Editor
National School of Public Health, Oswaldo Cruz Foundation, Av. Brasil, 4365 - Manguinhos, Rio de Janeiro 21040-900, Brazil
Interests: epidemiology; public policy; social inequalities; poverty; mortality; levels and trends; epidemiological transition and health transition; causes of death and its changes over long periods; inequality in the population's morbidity and mortality; cancer mortality and morbidity; life expectancy and longevity
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Institute of Collective Health, Federal University of Bahia, Salvador 30120-016, Brazil
Interests: epidemiology; public policy; social inequalities; poverty; systematic review with meta-analysis; population-attributable fractions (PAF) for a combination of cancer risk; nutritional transition

Special Issue Information

Dear Colleagues,

High cancer incidence rates are estimated for the coming decades, a worrying situation requiring significant investment in prevention, control, and treatment. This profile is due to greater exposure to environmental risk factors, population aging, and changes in reproductive behavior. Neoplasms have a high burden worldwide, with differences in incidence and mortality rates between countries. Cancers associated with infectious agents have a high incidence and mortality in low- and middle-income countries. On the other hand, in high-income countries, there is a greater burden of cancers associated with changes in reproductive behavior, the Westernization of habits, and lifestyle, a phenomenon classified as cancer transition. Inequalities in cancer survival between countries are also noteworthy due to better access to early diagnosis, timely treatment, and high-cost therapeutic innovations in high-income countries. These inequities are also observed at the subnational level, reflecting differences in the demographic and epidemiological transition process and inequalities in access to health services. This Special Issue, "Burden of Cancer Worldwide," seeks to explore differences in incidence, mortality, survival, access to cancer care, exposure to risk, and protective factors (individual, environmental, and contextual) across countries and at the subnational level.

Dr. Karina Cardoso Meira
Dr. Raphael Mendonça Guimarães
Dr. Nathalia Sernizon Guimarães
Guest Editors

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Keywords

  • mortality
  • morbidity
  • burden of cancer
  • social determinants of health
  • population-attributable fractions

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Published Papers (2 papers)

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Research

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11 pages, 1512 KiB  
Article
MPOWER Tobacco Control Policies’ Effects on Lip and Oral Cavity Cancer Trends in MERCOSUR Countries
by Laila Menezes Hagen, Fernanda Joly Macedo, Amanda Ramos da Cunha, Fernando Neves Hugo and José Miguel Amenábar
Int. J. Environ. Res. Public Health 2025, 22(4), 644; https://doi.org/10.3390/ijerph22040644 - 19 Apr 2025
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Abstract
Background: As tobacco is the main risk factor for oral cancer, it is important to understand the burden of this disease in light of the Framework Convention on Tobacco Control. For MERCOSUR, tobacco control is a topic of interest. The aim of this [...] Read more.
Background: As tobacco is the main risk factor for oral cancer, it is important to understand the burden of this disease in light of the Framework Convention on Tobacco Control. For MERCOSUR, tobacco control is a topic of interest. The aim of this study was to describe MPOWER measure scores and to evaluate the trends in lip and oral cavity cancer (LOC) incidence, mortality and Disability-Adjusted Life Years (DALYs), from 2005 to 2021, in MERCOSUR countries. Methods: This is an ecological descriptive study, where the MPOWER measure scores were extracted from the Global Health Observatory of World Health Organization, and the Age-standardized Rates (ASRs) of LOC for MERCOSUR countries were obtained from the Global Burden of Diseases 2021 results tool. The trends of LOC ASRs were obtained using the Prais–Winsten method. Results: Paraguay and Venezuela had lower MPOWER scores over time than Argentina, Brazil and Uruguay. These last three countries showed LOC trends decreasing for most indicators among males, while Paraguay and Venezuela showed increasing trends in incidence for both males and females, and no decreasing trends. Conclusion: This study suggests that MERCOSUR countries with a history of more rigorous MPOWER tobacco control policies are exhibiting decreasing trends in LOC burden. Full article
(This article belongs to the Special Issue Burden of Cancer Worldwide)
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Review

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13 pages, 1408 KiB  
Review
Diet and Oral Squamous Cell Carcinoma: A Scoping Review
by Marcela Gomes Reis, Lucas Carvalho Lopes, Ana Beatriz Amaral M. De A. Sanches, Nathalia Sernizon Guimarães and Roberta Rayra Martins-Chaves
Int. J. Environ. Res. Public Health 2024, 21(9), 1199; https://doi.org/10.3390/ijerph21091199 - 10 Sep 2024
Cited by 1 | Viewed by 1890
Abstract
Oral squamous cell carcinoma (OSCC) is the sixth most common type of cancer globally. While smoking is a key risk factor, rising cases in non-smokers highlight the need to explore other factors like diet. This scoping review aims to deepen the evidence on [...] Read more.
Oral squamous cell carcinoma (OSCC) is the sixth most common type of cancer globally. While smoking is a key risk factor, rising cases in non-smokers highlight the need to explore other factors like diet. This scoping review aims to deepen the evidence on the relationship between OSCC and diet, following PRISMA-ScR guidelines, and was registered on Open Science Framework. Searches were performed in four electronic databases: MEDLINE, Embase, Web of Science, and Lilacs, without date or language restrictions. Studies were evaluated, extracted, and compiled in a narrative table. Seventeen studies with 10,954 patients were analyzed. Most patients were male (74.63%), aged 18–89 (average 50.62). Studies were mainly from high (82%) and medium (17%) Human Development Index (HDI) countries. Dietary surveys included a Food Frequency Questionnaire (FFQ) (58.8%), interviews/questionnaires (17.6%), and an FFQ with a photographic atlas (5.9%). Certain foods in excess like fruits, vegetables, and tea were inversely associated with OSCC, while salty meats, dairy, coffee, sausages, and fried and spicy foods were positively associated. Due to the heterogeneity of the tools used to obtain food frequency data, the results should be interpreted cautiously. New standardized studies and randomized trials are essential to advance understanding and control confounding factors in this field. Full article
(This article belongs to the Special Issue Burden of Cancer Worldwide)
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