Special Issue "The Impact of the Gut Microbiota on Human Health"

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601).

Deadline for manuscript submissions: 31 December 2019.

Special Issue Editor

Guest Editor
Prof. Serena Schippa Website E-Mail
Università degli Studi di Roma La Sapienza, Rome, Italy
Interests: microorganism/host interactions; pathogenesis mechanisms; innovative therapies

Special Issue Information

Dear Colleagues,

Gut microbiota have taken a dominant role in the last decade as one of the major driving forces defining human health status. Gut microbiota composition includes bacteria, fungi, viruses, and Archaea, altogether peacefully coexisting in health. Evidence suggests that intestinal microbiota strongly influence the development and the functioning of many organs even far from the intestine, such as the brain, liver, and pancreas. Gut microbiota influence the development of the mucosal immune system and the enteric nervous system (ENS); effects on angiogenesis have also been recorded. The emerging field of the brain–gut axis and the direct/indirect action of the microbiota on ENS and the central nervous system (CNS) highlight its potential effect on extra intestinal health. All the functions of the intestinal microbiota are closely related to its equilibrium state/eubiosis. Several biotic (genetics, immune system, pathogens, and aging) and abiotic (xenobiotic, lifestyle, and drugs) features are able to affect gut microbiota composition, inducing a dysbiosis status. A growing number of pathologies are related to gut microbiota alteration, dysbiosis: Inflammatory bowel diseases (IBD), celiac disease, obesity, atopic allergies, and, ultimately, cognitive behavior and autism. The importance of gut microbiota composition for our health status has now veen established, and many therapies have been proposed to maintain/restore microbiota balance. I invite authors to submit original research and review articles focusing the Special Issue of the International Journal of Environmental Research and Public Health, entitled “The Impact of the Gut Microbiota on Human Health”. I am also interested in the role of single bacterial, fungus, virus, or Archaea species that may enhance their fitness within the gut upon biotic/abiotic stimuli. Potential manuscript topic include but are not limited to:

  • Gut microbiota impact on human health;
  • Diseases related to gut microbiota dysbiosis;
  • The ageing effect: Microbiota changes through the lifetime in health and disease ;
  • The brain–gut axis: How gut microbiota cross-talk with CNS and ENS;
  • Microbiota metabolic signatures in health and disease;
  • Rule of single bacterial, fungal or virus species impacting the composition of gut microbiota: Effect on human health;
  • Biotic/abiotic stimuli/factors impacting gut microbiota eubiotic status;
  • Therapeutics strategies to restore gut microbiota balance.

Prof. Serena Schippa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Gut Microbiota
  • Human health
  • Eubiosis/dysbiosis
  • Metabolic signatures
  • Bacterial, fungal or virus species of the gut
  • Therapeutic strategies

Published Papers

This special issue is now open for submission.
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