20 May 2021, Online
IJMS Webinar | Glioblastoma Intratumoral Heterogeneity and Plasticity
Glioblastoma multiforme (GBM) is the most aggressive type of brain cancer with a 5-year relative survival (4.6% only at 5 years) that has remained stable over the last 3 decades. Intratumour heterogeneity is a key feature that makes GBM one of the most deadly types of tumours, which results from the capacity of GBM-cancer stem cells to inter-convert between different cancer cell populations in response to changes in the tumour microenvironment and/or different drug treatments. This not only explains the poor performance in single drug therapy in GBM, but also reveals a key role for GBM plasticity, the interaction of GBM and the microenvironment and brain cancer progression, and thus constitutes a novel paradigms that needs to be addressed in order to find better treatments for patients with GBM.
This webinar features three glioblastoma experts covering researches into molecular level of the functional role of heterogeneity and plasticity in glioblastoma biology and treatment.
- Dr. Guillermo Gomez, SA Pathology and University of South Australia, Adelaide, Australia
- Ms. Maria Jose Gattas, Universidad Nacional de San Martín, Buenos Aires, Argentina
- Prof. Dr. Bryan Day, QIMR Berghofer Medical Research Institute, Brisbane, Australia
When? 20 May 2021 at 1.30am CEST | 9.00am ACST
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