Imaging Vascular Infection and Inflammation by FDG-PET/CT or Radiolabelled White Blood Cells

A special issue of Hemato (ISSN 2673-6357). This special issue belongs to the section "Radiolabeled Blood Elements and Other Imaging Modalities".

Deadline for manuscript submissions: closed (15 November 2023) | Viewed by 1636

Special Issue Editors


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Guest Editor
Department of Surgical-Medical Sciences and Translational Medicine, University of Rome “Sapienza”, Rome, Italy
Interests: nuclear medicine; infection imaging; inflammation imaging; thyroid cancer imaging; pre-clinical imaging; imaging immuno-therapy; imaging autoimmune diseases
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Guest Editor
Division of Nuclear Medicine, Department of Oncology and Advanced Technology, S.Maria Nuova Hospital, AUSL-IRCCS (Research Cancer Institute) of Reggio Emilia, Viale Risorgimento, 80 42123 Reggio Emilia, Italy
Interests: nuclear medicine; PET/CT; inflammation/infection imaging; thyroid cancer imaging and therapy; neuroendocrine tumor imaging and therapy; lymphoma imaging; multiple myeloma imaging

Special Issue Information

Dear Colleagues,

This Special Issue aims at providing a panoramic overview of current and future strategies for imaging vascular infections and inflammation. Both conditions still represent a challenge for clinicians and require a prompt diagnosis and initiation of adequate treatment.

Nuclear medicine imaging has rapidly gained a role in the field of infection and inflammation, and it is currently included in most of the diagnostic flowcharts for the diagnosis of vasculitis, vascular graft infections and cardiovascular infections. For some of these indications, specific interpretation criteria, able to allow an accurate diagnosis, have been published for both [18F]FDG PET/CT and radiolabelled white blood cells scintigraphy, thereby improving therapy planning; for some other clinical indications, standardized protocols of image acquisition and interpretation are still needed and deserve further prospective and comparative studies.

This Special Issue will be, therefore, focused on the possible application of [18F]FDG PET/CT and radiolabelled white blood cells scintigraphy for imaging atherosclerosis, vasculitis, vascular graft infections and other haematological conditions. In particular, it will collect papers exploring the potential of nuclear medicine imaging in the diagnostic setting of these situations as well as for monitoring disease activity after a proper treatment.

Prof. Dr. Alberto Signore
Dr. Annibale Versari
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Hemato is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • FDG
  • PET-CT
  • SPECT
  • radiolabelled white blood cells
  • atherosclerosis
  • vasculitis
  • vascular grafts
  • inflammation
  • infection
  • haematological disorders

Published Papers (1 paper)

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Review

16 pages, 7345 KiB  
Review
Imaging of Vascular Graft/Endograft Infection with Radiolabeled White Blood Cell Scan and [18F]FDG PET/CT
by Ringo Manta, Chiara Lauri, Maurizio Taurino and Alberto Signore
Hemato 2023, 4(4), 285-300; https://doi.org/10.3390/hemato4040023 - 22 Sep 2023
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Abstract
Diagnosis of vascular graft/endograft infection (VGEI) is a challenge for clinicians due to the heterogeneity of clinical presentation and the complexity of its management. Microbiological culture is the gold standard, but it often fails to isolate the causative microorganism. A non-invasive imaging approach [...] Read more.
Diagnosis of vascular graft/endograft infection (VGEI) is a challenge for clinicians due to the heterogeneity of clinical presentation and the complexity of its management. Microbiological culture is the gold standard, but it often fails to isolate the causative microorganism. A non-invasive imaging approach is therefore needed to assess VGEI. CTA is currently the first-choice imaging modality. Nuclear medicine techniques are recommended in case of negative or doubtful CTA results with persisting clinical suspicion. This review aims to summarize data from original studies published in the last decades regarding the role of both white blood cell (WBC) scans and fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography ([18F]FDG PET/CT), their respective diagnostic performances, and their integration into the diagnostic approach for patients with a suspicion of VGEI. Full article
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