Reviews on Critical Care

A special issue of Healthcare (ISSN 2227-9032). This special issue belongs to the section "Critical Care".

Deadline for manuscript submissions: 15 May 2025 | Viewed by 3242

Special Issue Editor


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Guest Editor
Faculty of Medicine, The University of Queensland, Herston 4006, Australia
Interests: anaesthesia; airway management; videolaryngoscopy; regional anaesthesia; obstetric anaesthesia; historical articles on anaesthesia

Special Issue Information

Dear Colleagues,

The aim of the Special Issue is to cover a broad spectrum of clinical care clinical practices and basic research advances and innovations in clinical anesthesia, intensive care, and emergency medicine. It also can include the impact of anesthesia, intensive care and emergency care on the environment and the impact of frailty on postoperative outcome. The Special Issue hopes to bring together healthcare specialists who treat patients in the operating room, intensive care unit, and emergency department, and other healthcare professionals. We hope to provide an open and friendly platform and space for the exchange and share of ideas and views on the management of the critically ill patients, offering in-depth coverage of this specialty.

In this Special Issue, reviews are welcome. Research areas may include (but are not limited to) the following:

  • Anaesthesia;
  • Intensive care;
  • Critical care;
  • Critically ill;
  • Critical care medicine;
  • Mechanical ventilation;
  • Hemodynamic monitoring;
  • Cardiac support;
  • Renal replacement therapy;
  • Fluid management;
  • Pain management;
  • Shock;
  • Sepsis;
  • Infections;
  • Traumatic brain/spinal injury;
  • Vasoactive drugs;
  • Parenteral nutrition;
  • Cardiac failure;
  • Ischemic heart disease;
  • Respiratory failure;
  • Sedation.

We look forward to receiving your contributions.

Prof. Dr. Andre van Zundert
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

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Published Papers (2 papers)

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Review

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16 pages, 1323 KiB  
Review
The Internet, Apps, and the Anesthesiologist
by Samuel Smith, Andrew Houghton, Brydie Mockeridge and André van Zundert
Healthcare 2023, 11(22), 3000; https://doi.org/10.3390/healthcare11223000 - 20 Nov 2023
Cited by 2 | Viewed by 1634
Abstract
Modern anesthesia continues to be impacted in new and unforeseen ways by digital technology. Combining portability and versatility, mobile applications or “apps” provide a multitude of ways to enhance anesthetic and peri-operative care. Research suggests that the uptake of apps into anesthetic practice [...] Read more.
Modern anesthesia continues to be impacted in new and unforeseen ways by digital technology. Combining portability and versatility, mobile applications or “apps” provide a multitude of ways to enhance anesthetic and peri-operative care. Research suggests that the uptake of apps into anesthetic practice is becoming increasingly routine, especially amongst younger anesthetists brought up in the digital age. Despite this enthusiasm, there remains no consensus on how apps are safely and efficiently integrated into anesthetic practice. This review summarizes the most popular forms of app usage in anesthesia currently and explores the challenges and opportunities inherent in implementing app use in anesthesia, with an emphasis on a practical approach for the modern anesthetist. Full article
(This article belongs to the Special Issue Reviews on Critical Care)
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13 pages, 2775 KiB  
Systematic Review
The Effectiveness and Safety of Tranexamic Acid in Treating Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis
by Mohammed O. Al Zayer, Fatima M. Al Johani, Shahad A. Al ghamdi, Mohammed D. Al Hejaili, Fatima H. Al Mukhtar, Arwa M. Al Ariany, Bashar H. Al Anazi, Khalid A. Al Mutairi, Rammaz H. Khoja, Haidar F. Al Amer, Adel A. Zeidan and Dunya Al Faraj
Healthcare 2024, 12(23), 2452; https://doi.org/10.3390/healthcare12232452 - 5 Dec 2024
Viewed by 1073
Abstract
Background/Objectives: Tranexamic acid (TXA) is a synthetic antifibrinolytic agent that inhibits plasminogen activation, thereby reducing bleeding. The aim of this systematic review was to investigate its role in aneurysmal subarachnoid hemorrhage (SAH)—a condition indicated by bleeding between two layers of brain tissue—to stop [...] Read more.
Background/Objectives: Tranexamic acid (TXA) is a synthetic antifibrinolytic agent that inhibits plasminogen activation, thereby reducing bleeding. The aim of this systematic review was to investigate its role in aneurysmal subarachnoid hemorrhage (SAH)—a condition indicated by bleeding between two layers of brain tissue—to stop rebleeding and improve patient outcomes. Methods: We conducted a systematic review and meta-analysis of randomized controlled trials from 1981 to 2024, focusing on the efficacy and safety of TXA in treating aneurysmal SAH (PROSPERO registration: CRD42024504834). Our comprehensive search of the PubMed and Cochrane Library databases identified studies assessing TXA at dosages of 3 to 6 g per day and examining outcomes such as rebleeding incidence, mortality, thromboembolic events, and other adverse effects. Results: From six included studies involving 2990 patients, the meta-analysis showed TXA largely lowered rebleeding risk (OR 0.54 95% CI 0.43–0.68; p < 0.00001), yet mortality rates were not largely different between the TXA group (385 out of 1201), and the control group (344 out of 1193) (OR 1.18 95% CI 0.98–1.40; p = 0.07). Likewise, there were no large differences in the occurrence of cerebral ischemia and blood clot-related events between the groups. Conclusions: TXA effectively reduces the risk of rebleeding in SAH patients, but does not significantly alter mortality or the incidence of thromboembolic complications. These findings back the careful use of TXA and demonstrate the need for further research to better its clinical use and assess long-term impacts. Full article
(This article belongs to the Special Issue Reviews on Critical Care)
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