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Advancing Clinical and Translational Research in Healthcare: From Innovation to...
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Advancing Clinical and Translational Research in Healthcare: From Innovation to Implementation and Impact

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: 21 May 2027 | Viewed by 387

Editors

Prof. Dr. Lorraine S. Evangelista

E-Mail Website
Guest Editor
Sue & Bill Gross School of Nursing, University of California, Irvine, CA 92697, USA
Interests: clinical and translational research; implementation science; workforce development/training; learning health systems; real-world evidence; dissemination and implementation (D&I); quality improvement; team science/interdisciplinary collaboration
Dr. Francisco S. Sy

E-Mail Website
Guest Editor
Department of Environmental and Global Health, School of Public Health, University of Nevada, Las Vegas, NV 89119, USA
Interests: health disparity research; community-based participatory research (CBPR); infectious disease epidemiology; workforce development/capacity building; public health systems; team science and collaborative research

Special Issue Information

Dear Colleagues,

Even with significant progress in clinical and public health research, putting evidence into practice remains a major global challenge. Clinical and translational research (CTR) is crucial in addressing this issue by developing strategies that facilitate the translation of evidence from initial discovery to practical application, thereby enhancing patient outcomes and the overall effectiveness of health systems. As a result, this process requires not only technical solutions but also collaboration across fields, workforce training, and implementation strategies tailored to specific situations.

This Special Issue will highlight fresh, pragmatic viewpoints that broaden the reach of clinical and translational research within diverse healthcare environments. We especially encourage submissions that examine how evidence-based interventions are adapted, implemented, and sustained in the real world. These settings include healthcare systems, educational institutions, and community organizations. We are especially interested in research that uses implementation science, workforce development, digital health, and interdisciplinary collaboration to address complex health challenges.

We welcome original research, along with systematic and scoping reviews, implementation studies, case reports, and commentaries. We are especially looking for work that offers practical advice for those in the trenches: clinicians, researchers, educators, and policymakers. This Special Issue will promote scalable, sustainable approaches. Our goal is to improve the ways in which evidence is put into practice and to support the global transformation of health systems.

We look forward to receiving your contributions.

Prof. Dr. Lorraine S. Evangelista
Dr. Francisco S. Sy
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • clinical and translational research (CTR)
  • translational science (T1–T4)
  • implementation science
  • dissemination and implementation research
  • health services research
  • patient-centered outcomes
  • evidence-based practice
  • digital health
  • artificial intelligence in healthcare
  • patient education
  • health communication
  • health equity
  • community-based interventions

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

17 pages, 1223 KB  
Article
Beyond the Silence: COM-B-Informed Provider Barriers to Depression Screening Among Filipino American Patients
by Miguel Antonio Fudolig, Andrew Thomas Reyes, Franz Henryk Vergara, Marlon Garzo Saria, Erwin William Leyva, Lorraine S. Evangelista and Reimund Serafica
Healthcare 2026, 14(14), 2166; https://doi.org/10.3390/healthcare14142166 - 17 Jul 2026
Viewed by 244
Abstract
Background/Objectives: Routine depression screening is recommended in primary care, yet depression may remain underdetected among Filipino American patients. Provider-level factors, including culturally responsive preparation, communication challenges, workflow constraints, and attitudes toward mental health screening, may influence opportunities for early identification and referral. This [...] Read more.
Background/Objectives: Routine depression screening is recommended in primary care, yet depression may remain underdetected among Filipino American patients. Provider-level factors, including culturally responsive preparation, communication challenges, workflow constraints, and attitudes toward mental health screening, may influence opportunities for early identification and referral. This exploratory cross-sectional study examined provider perspectives on barriers to depression screening and mental health discussions with Filipino American patients using the Capability, Opportunity, Motivation, and Behavior (COM-B) framework as an implementation-informed organizing lens. Methods: A cross-sectional survey was conducted among healthcare providers (N = 81) with experience caring for Filipino American patients in the United States. Survey items assessed provider confidence, perceived adequacy of mental health training, cultural and communication barriers, perceived stigma-related concerns, comfort discussing mental health, and interest in additional culturally responsive resources. Items from the adapted Attitudes Toward Assisting Filipino American Patients with Mental Health Symptoms (ATFA) scale and one item from the Mental Illness Clinicians’ Attitudes scale were conceptually mapped to the COM-B domains. Descriptive statistics, internal consistency estimates, and nonparametric tests were used to summarize findings and explore differences by provider characteristics. Results: Most providers recognized that Filipino cultural beliefs and customs may influence mental health help-seeking and symptom expression. Although many providers reported confidence identifying mental health symptoms, fewer reported adequate training to assess mental health concerns among Filipino American patients. Communication barriers, stigma-related concerns, and interest in additional culturally tailored resources were commonly reported. COM-B domain scores were not significantly associated with provider role or years of clinical experience. Providers who identified as Filipino reported greater perceived capability and opportunity related to initiating mental health discussions compared with non-Filipino providers. Conclusions: Findings suggest that provider motivation to address mental health concerns may be present, while capability- and opportunity-related barriers, including culturally responsive training, communication support, workflow integration, and referral resources, may remain important targets for future implementation efforts. Because this exploratory study used a modest convenience sample and an adapted measure that requires further psychometric validation, the findings should be interpreted with caution. Larger studies using validated instruments are needed to examine further provider-level determinants of culturally responsive depression screening among Filipino American patients. Full article
(This article belongs to the Special Issue Advancing Clinical and Translational Research in Healthcare: From Innovation to Implementation and Impact)
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