Genetics and Genomics of Aging and Dementia

Dear Colleagues,

The study of genetic information on the biological mechanisms involved in cognitive decline has become increasingly relevant and received much attention in recent years, focusing the search for new genetic biomarkers that allow early diagnosis and in turn characterize the population at risk of developing some type of neurological disease that occurs with aging.

Dementia is characterized by severe memory loss and cognitive impairment, resulting in complete dependency and reduced life expectancy. Genetic studies have shown us that some genetic variants have linked both haplogroups and mitochondrial variants with the development of aging and the chronic diseases that characterize it, such as dementia. In addition to some polymorphisms, mutations, and haplogroups, there is another risk factor that plays an important role in the regulation, development, and prognosis of chronic-degenerative diseases such as Alzheimer's and other dementias.

In this Special Issue, we would like to invite submissions of original research or review articles on topics relevant to "Genetics and Genomics of Aging and Dementia". We hope to contribute to the knowledge of the genetic mechanisms involved in aging that trigger cognitive decline and lead us to dementia to propose new therapeutic strategies that allow maintaining the functionality of populations. We look forward to receiving your contributions.

Prof. Dr. Teresa Juárez-Cedillo
Prof. Dr. Alfredo Ramirez
Guest Editors

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