Special Issue "Genetic Basis of Phenotypic Variation in Drosophila and Other Insects"
Deadline for manuscript submissions: closed (29 February 2020).
Interests: genome size evolution; evolution of mobile elements; genomics
Interests: sex chromosome evolution; heterochromatin; underreplication; genome size
The wealth of genomic sequence data generated on an ever-increasing number of species has no road map. How sequences generate the observed diversity of living forms remains largely unanswered. The diversity in coding sequences is responsible some of this diversity, but the degree to which it contributes is unclear. Coding and non-coding sequences are involved in a network of interactions which can change the level of expression and change the timing of that expression, creating further diversity. Novel phenotypes emerge from these interactions, and the diversity this generates may be further altered by interactions with the environment.
Tools to untangle the sources of diversity have been developed. Most rely upon comparisons of the sequence and phenotypic differences among strains and species. Frequently, these tools take advantage of the sequence quality of the Drosophila genome, the local and global variety of generated Drosophila melanogaster strains, and the even greater range of phenotypes among species in the genus. Adding to this are studies that compare the Drosophila genomic sequence to that of insects with unique phenotypic adaptations. The multiple authors of the Special Issue are among the leaders in this effort, and share their contributions towards generating a road map connecting the gene networks and phenotypic diversity created by genetic and environmental change.
Prof. J. Spencer Johnston
Dr. Carl E. Hjelmen
Manuscript Submission Information
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- gene networks
- quantitative genomics
- Drosophila strains
- Drosophila species
- local adaptation