Special Issue "Molecular Risk Factors of Complex Diseases"
Deadline for manuscript submissions: closed (31 March 2021).
Complex diseases (multifactorial diseases) are diseases with a strong genetic component and a defined background of environmental factors. Complex diseases form a large group of disorders, with particular emphasis on civilization diseases and autoimmune diseases, which are highly problematic in modern medicine. The most characteristic features of complex diseases include the lack of the standard Mendelian patterns of inheritance and the broad spectrum of common candidate genes that may be genetic risk factors for these diseases. A strong genetic component in complex diseases is visible in occurrences inside of families and in the studies of monozygotic twins. Defining the molecular background of this group of diseases taking into account population differences may be important to improving diagnostic procedures and defining risk groups and may influence the individualization of treatment (pharmacogenetics) and a determination on prognosis. The high population prevalence of complex diseases is, therefore, the main motivation for the search for genetic and environmental components of their etiology.
This Special Issue of Genes on “Molecular Risk Factors of Complex Diseases” will be dedicated to researchers who are looking to confirm the genetic background of multifactorial diseases. It aims to review and discuss the latest research in this field and assist with the take-up of new ideas and research directions.
Dr. Natalia Wawrusiewicz-Kurylonek
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- multifactorial diseases
- genetic background
- single nucleotide variants
- susceptibility regions in genomes
- candidate genes
- potential molecular risk factors