Genetic Markers and Liquid Biopsy for Kidney Diseases
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: closed (15 June 2024) | Viewed by 20233
Special Issue Editors
Interests: molecular markers; liquid biopsy; renal cell carcinomas; liquid biopy technology; urological cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the modern era, technical advances in molecular biology have proven successful in the understanding of the pathogenesis of kidney diseases. The recent advents of next-generation sequencing and high-throughput functional genomics techniques have allowed us to produce molecular fingerprints that characterize the expressions of genes within different kidney cells. As a result, significant molecular markers have been found among kidney diseases.
However, many kidney diseases such as rejection of kidney transplantation, kidney cancer, IgA nephropathy and other chronic kidney diseases are still diagnosed by kidney tissue biopsy. This tissue biopsy is invasive and can introduce some serious complications. Liquid biopsy analyzes biomarkers in bodily fluids. Liquid biopsies are preferable to tissue biopsies because they are less invasive. Liquid biopsy technologies based on circulating DNA/RNA, extracellular vesicles and exosomes have been explosive. The analysis of gene expressions by liquid biopsy technology represents a promising new avenue for the diagnosis and prognosis of kidney diseases.
This Special Issue in Genes titled “Genetic Markers and Liquid Biopsy for Kidney Diseases” will provide a monographic portrait of the current advances in molecular biomarkers and liquid biopsy technology for the clinical management of kidney diseases including kidney cancer, kidney transplantation, nephropathy and chronic kidney disease. We especially welcome review articles (either systematic or discursive), mini-reviews, new methods, original research studies and short communications of preliminary, but significant, experimental results.
Prof. Dr. Guorong Li
Prof. Dr. Christophe Mariat
Guest Editors
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Keywords
- molecular markers
- renal cell carcinoma
- kidney transplantation
- nephropathy
- chronic kidney disease
- acute kidney injury
- kidney biopsy
- liquid biopsy
- liquid biopsy technology
- circulating DNA or RNA
- extracellular vesicles
- exosomes
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