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Journals
Genes
Special Issues
Emerging and Reemerging Viral Pathogens
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Emerging and Reemerging Viral Pathogens

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Microbial Genetics and Genomics".

Deadline for manuscript submissions: closed (25 July 2023) | Viewed by 3245

Special Issue Editors

Dr. Vagner Fonseca

E-Mail Website
Guest Editor
Department of Exact and Earth Sciences, University of the State of Bahia, Salvador 41150-000, Brazil
Interests: bioinformatics; viral evolution; molecular epidemiology; mathematical models; phylogenetic and phylodynamic trees
Special Issues, Collections and Topics in MDPI journals
Dr. Marta Giovanetti

E-Mail Website
Guest Editor
1. Sciences and Technologies for Sustainable Development and One Health, University Campus Bio-Medico of Roma, 00128 Rome, Italy
2. Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil
Interests: emerging and re-emerging viral pathogens; molecular evolution; genomic epidemiology; phylodynamics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We invite you to contribute your most recent research findings and insights in the form of original research papers, technical advancements, or review articles to this Special Issue of Genes entitled “Emerging and Reemerging Viral Pathogens”. In this Special Issue, we aim to provide new genomic data on viral strains circulating worldwide, and to overview the real-time global evolution of viruses.

Dr. Vagner Fonseca
Dr. Marta Giovanetti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioinformatics tools
  • genome evolution
  • phylogenetic tree
  • mathematical modeling

Published Papers (1 paper)

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Research

15 pages, 4754 KiB  
Article
Molecular Epidemiology and Diversity of SARS-CoV-2 in Ethiopia, 2020–2022
by Abay Sisay, Derek Tshiabuila, Stephanie van Wyk, Abraham Tesfaye, Gerald Mboowa, Samuel O. Oyola, Sofonias Kifle Tesema, Cheryl Baxter, Darren Martin, Richard Lessells, Houriiyah Tegally, Monika Moir, Jennifer Giandhari, Sureshnee Pillay, Lavanya Singh, Yajna Ramphal, Arisha Maharaj, Yusasha Pillay, Akhil Maharaj, Yeshnee Naidoo, Upasana Ramphal, Lucious Chabuka, Eduan Wilkinson, Tulio de Oliveira, Adey Feleke Desta and James E. Sanadd Show full author list remove Hide full author list
Genes 2023, 14(3), 705; https://doi.org/10.3390/genes14030705 - 13 Mar 2023
Cited by 4 | Viewed by 2966
Abstract
Ethiopia is the second most populous country in Africa and the sixth most affected by COVID-19 on the continent. Despite having experienced five infection waves, >499,000 cases, and ~7500 COVID-19-related deaths as of January 2023, there is still no detailed genomic epidemiological report [...] Read more.
Ethiopia is the second most populous country in Africa and the sixth most affected by COVID-19 on the continent. Despite having experienced five infection waves, >499,000 cases, and ~7500 COVID-19-related deaths as of January 2023, there is still no detailed genomic epidemiological report on the introduction and spread of SARS-CoV-2 in Ethiopia. In this study, we reconstructed and elucidated the COVID-19 epidemic dynamics. Specifically, we investigated the introduction, local transmission, ongoing evolution, and spread of SARS-CoV-2 during the first four infection waves using 353 high-quality near-whole genomes sampled in Ethiopia. Our results show that whereas viral introductions seeded the first wave, subsequent waves were seeded by local transmission. The B.1.480 lineage emerged in the first wave and notably remained in circulation even after the emergence of the Alpha variant. The B.1.480 was outcompeted by the Delta variant. Notably, Ethiopia’s lack of local sequencing capacity was further limited by sporadic, uneven, and insufficient sampling that limited the incorporation of genomic epidemiology in the epidemic public health response in Ethiopia. These results highlight Ethiopia’s role in SARS-CoV-2 dissemination and the urgent need for balanced, near-real-time genomic sequencing. Full article
(This article belongs to the Special Issue Emerging and Reemerging Viral Pathogens)
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