Advances in Genetic Variants in Neurological and Psychiatric Diseases
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Human Genomics and Genetic Diseases".
Deadline for manuscript submissions: 10 January 2026 | Viewed by 22
Special Issue Editor
Special Issue Information
Dear Colleagues,
Genetic research utilizing large datasets has elucidated the multifactorial causes of neurological and psychiatric disorders, marked by significant heritability and high levels of polygenicity.
Epidemiological studies emphasize significant comorbidity among various neurological and psychiatric conditions, indicating shared environmental risk factors and genetic mechanisms.
The extent to which these conditions share a common origin remains uncertain.
Additional research—including meta-analyses of genome-wide association studies (GWASs), polygenic risk scoring, and transcriptomic analyses, as well as network-based approaches—is needed to clarify the underlying causes of the observed comorbidity. This Special Issue aims to advance the understanding of this subject by fostering research that investigates the genetic framework of neurological and psychiatric disorders, either individually or in combination.
Dr. Evelina Mocci
Guest Editor
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Keywords
- pleiotropy
- comorbidity
- meta-analysis
- polygenic risk score
- transcriptome
- network analysis
- psychiatric
- neurology
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