Engineering Advanced Hydrogels for Biomedical Applications (2nd Edition)

Dear Colleagues,

Hydrogels are attractive scaffolds that hold a significant amount of water in their 3D structure and are similar to our body tissues in terms of mechanical properties and biocompatibility. They can be widely used in biomedical applications, including drug delivery, tissue engineering, and regenerative medicine. However, conventional hydrogels have several limitations, such as a lack of multifunctionality. As a result, advanced hydrogels have been developed and engineered to address a variety of difficult therapeutic demands (e.g., infected wounds, diabetic wounds, or trauma wound treatment). Recently formed hydrogels can be multifunctional and exhibit high mechanical, bio-adhesive, antibacterial, and antioxidant capabilities. In particular, smart hydrogels may be created by combining multifunctional hydrogels with various bioactive compounds, such as cytokines, immunomodulatory substances, or growth factors. With the ability to modulate both innate and adaptive immune responses, promote chronic wound healing, and ultimately lead to scarless tissue regeneration, advanced multifunctional hydrogels can even provide spatiotemporal control over immune responses. Furthermore, cutting-edge methods including 3D printing, microfluidics, and microneedles can be used to enhance sophisticated multifunctional hydrogels. The numerous bio-applications of cutting-edge multifunctional hydrogels as well as their engineering techniques will be covered in this Special Issue.

We anticipate receiving active submissions on the broad topic of developing advanced hydrogels with multiple functionalities for biomedical applications. It gives us great pleasure to extend an invitation to you to submit a paper for this Special Issue, which is open to brief communications, case reports, reviews, and original research articles.

Dr. Bae Hoon Lee
Dr. Nabila Mehwish
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gels is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• hydrogels
• immunoregulation
• multifunctional properties
• polymers
• nanocomposites
• tissue regeneration
• wound healing
• bioprinting
• drug delivery
• cell culture

• Engineering Advanced Hydrogels for Biomedical Applications in Gels (5 articles)