Nanocellulose Hydrogels and Aerogels as Smart Sensing Platforms

A special issue of Fibers (ISSN 2079-6439).

Deadline for manuscript submissions: 30 June 2026 | Viewed by 1637

Special Issue Editor


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Guest Editor
Institute of Chemistry of Renewable Resources, Department of Natural Sciences and Sustainable Resources, Universität für Bodenkultur Wien, 3430 Tulln, Austria
Interests: biopolymers; cellulose; lignin; biobased gels and porous materials; aerogels; supercritical carbon dioxide; green chemistry
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Special Issue Information

Dear Colleagues,

Anisometric cellulose nanocrystals, nanofibrils, nanospheres, and nanosheets are fascinating building blocks for creating smart functional hydrogels and aerogels that can even feature directional properties. The latter rely on the intriguing ability of cellulose nanoparticles to self-align in an aqueous dispersion state in different ‘liquid–crystalline’ orientations, which affords gels of different network morphologies that can be designed to respond to physical–chemical stimuli. The properties of respective gels (or derived aerogels) can be further modulated by physical and chemical (stimuli-responsive reversible) crosslinking, such as with inorganic nanoparticles like clay minerals, metal–organic frameworks, networks of (semi-) interpenetrating secondary organic polymers, or by modification with functional groups or nanoparticles capable of reporting specific interactions with target analytes, electromagnetic irradiation, or magnetic fields.

This wealth of opportunities for manipulating the properties of nanocellulose hydrogels and aerogels along with their compliance to aspects of the green chemistry philosophy have recently paved the way regarding  the use of nanocellulose in many established and novel applications, including bioimaging, photonic, optical, and electrical (bio)sensing, as well as in materials capable of responding to physical–chemical stimuli (pH, humidity, and mechanical stress).

This Special Issue intends to provide a platform for the publication of the most recent original works and findings in nanocellulose-based sensor systems.

Prof. Dr. Falk Liebner
Guest Editor

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Keywords

  • nanocellulose
  • hydrogels
  • aerogels
  • sensing
  • sensor platform
  • stimuli responsive
  • cellulose nanocrystals
  • cellulose nanofibrils
  • smart hydrogels

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Published Papers (1 paper)

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Review

16 pages, 805 KB  
Review
Highly Porous Cellulose-Based Scaffolds for Hemostatic Devices and Smart Platform Applications: A Systematic Review
by Nikita A. Shutskiy, Aleksandr R. Shevchenko, Ksenia A. Mayorova, Leonid L. Shagrov and Andrey S. Aksenov
Fibers 2026, 14(1), 9; https://doi.org/10.3390/fib14010009 - 5 Jan 2026
Cited by 1 | Viewed by 976
Abstract
A promising application of smart materials based on natural polymers is the potential to solve problems related to hemostasis in cases of severe bleeding caused by injury or surgery. This can be a life-threatening situation. Cellulose and its modified derivatives represent one of [...] Read more.
A promising application of smart materials based on natural polymers is the potential to solve problems related to hemostasis in cases of severe bleeding caused by injury or surgery. This can be a life-threatening situation. Cellulose and its modified derivatives represent one of the most promising sources for creating effective hemostatic systems, as well as for various sensing applications related to disease detection, infection diagnosis, chronic condition monitoring, and blood analysis. The aim of this review was to identify key criteria for the efficiency of cellulose-based gels with hemostatic activity. Experimental studies aimed at evaluating new hemostatic devices were analyzed based on international sources using the PRISMA methodology. A total of 111 publications were identified. Following the identification and screening stages, 20 articles were selected for the final qualitative synthesis. The analyzed publications include experimental studies focused on the development and analysis of highly porous cellulose-based scaffolds in the form of aerogels and cryogels. The type and origin of cellulose, as well as the influence of additional components and synthesis conditions on gel formation, were investigated. Three major groups of key criteria that should be considered when developing new cellulose-based highly porous scaffolds with hemostatic functionality were identified: (I) physicochemical and mechanical properties (pore size distribution, compressive strength, and presence of functional groups); (II) in vitro tests (blood clotting index, red blood cell adhesion rate, hemolysis, cytocompatibility, and antibacterial activity); (III) in vivo hemostatic efficiency (hemostasis time and blood loss) in compliance with the 3Rs policy (replacement, reduction, refinement). The prospects for the development of highly porous cellulose-based scaffolds are not only focused on their hemostatic properties, but also on the development of smart platforms. Full article
(This article belongs to the Special Issue Nanocellulose Hydrogels and Aerogels as Smart Sensing Platforms)
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