Metabolic Engineering, Strain Modification and Industrial Application
A special issue of Fermentation (ISSN 2311-5637). This special issue belongs to the section "Microbial Metabolism, Physiology & Genetics".
Deadline for manuscript submissions: 30 October 2025 | Viewed by 93
Special Issue Editor
Special Issue Information
Dear Colleagues,
Microorganisms, as efficient biosynthetic platforms, have demonstrated tremendous application potential in many fields such as food, pharmaceuticals, energy, and chemicals. Metabolically engineered microorganisms, through the systematic design and optimization of metabolic networks, have significantly enhanced the synthesis efficiency of target products and endowed microorganisms with new biological functions, thus providing a strong scientific foundation and technological support for the innovation of industrial biotechnology.
In recent years, research in metabolic engineering and strain improvement have made groundbreaking progress with the rapid development of genome editing technologies (e.g., the CRISPR-Cas system), multi-omics techniques (including genomics, transcriptomics, proteomics, and metabolomics), and artificial intelligence technologies. These technologies have not only deepened our understanding about the mechanism in metabolism and regulation but have also provided novel solutions for the construction and performance optimization of industrial strains. In addition, the integration and application of these technologies have accelerated the design and development of novel biosynthetic pathways, thus enabling microorganisms to produce more complex and high-value compounds, such as natural products, bio-based materials, and high-performance chemicals. This has opened new avenues for the in-depth development and industrial application of microbial resources.
This Special Issue aims to publish the latest innovative research and review articles on metabolic engineering, strain improvement, and their industrial applications. We hope that the reports published in this Special Issue will promote academic exchange and technological advancement in this field.
Dr. Jianzhong Xu
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fermentation is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metabolic engineering
- synthetic biology
- strain improvement
- industrial applications
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