Oral Implantology and Bone Regeneration: 2nd Edition

A special issue of Dentistry Journal (ISSN 2304-6767). This special issue belongs to the section "Dental Implantology".

Deadline for manuscript submissions: 25 November 2026 | Viewed by 218

Special Issue Editors


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Guest Editor
Department of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy
Interests: bone regeneration soft tissue management; oral implants
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
School of Dentistry, University of Sassari, 07100 Sassari, Italy
Interests: fixed prosthesis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is focused on oral implantology and guided bone regeneration. Clinical articles and case reports, as well as retrospective studies, are welcome that focus on regeneration and computer-assisted oral implantology topics. The aim of this Special Issue is to implement and share knowledge on gold standards and new approaches in oral implantology.

Prof. Dr. Silvio Mario Meloni
Dr. Milena Pisano
Guest Editors

Manuscript Submission Information

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Keywords

  • implant dentistry
  • bone regeneration
  • bone reconstruction
  • fixed prosthodontics
  • oral surgery
  • oral implantology

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Related Special Issue

Published Papers (1 paper)

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Review

15 pages, 4257 KB  
Review
Osteo-Inductive Strategies for Enhancing Osseointegration and Optimizing Peri-Implant Emergence Profile: A Narrative Review
by Ioan Sirbu, Elisei Adelin Radu, Andy Radu Leibovici, Andreea Mihaela Custura, Ruxandra Stanescu, Alexandra Tuta, Vladimir Nastasie and Valentin Daniel Sirbu
Dent. J. 2026, 14(5), 310; https://doi.org/10.3390/dj14050310 - 18 May 2026
Abstract
Background: Osteoinduction and bone regeneration are fundamental biological mechanisms enabling osseointegration and long-term durability of endosseous dental implants. In clinical practice, poor bone conditions, aesthetic demands, and peri-implant soft tissue problems commonly need the utilization of regenerative techniques targeted at optimizing both hard [...] Read more.
Background: Osteoinduction and bone regeneration are fundamental biological mechanisms enabling osseointegration and long-term durability of endosseous dental implants. In clinical practice, poor bone conditions, aesthetic demands, and peri-implant soft tissue problems commonly need the utilization of regenerative techniques targeted at optimizing both hard and soft tissue results. The purpose of this narrative review was to examine osteo-inductive and regenerative strategies currently employed in implant dentistry, with particular emphasis on the mechanobiological integration of hard–soft tissue regeneration and its implications for peri-implant tissue stability, osseointegration, and clinical predictability. Methods: A narrative literature review was done using PubMed and Scopus databases. Based on predetermined inclusion and exclusion criteria, studies published in English during the previous five years were reviewed. The core narrative analysis comprised a selection of physiologically relevant research that addressed osteo-inductive techniques, bone regeneration, osseointegration, and peri-implant soft tissue outcomes, as well as clinical studies, randomized controlled trials, systematic reviews, and narrative reviews. A narrative synthesis was carried out because of methodological variability. Special emphasis was placed on evidence addressing the biological and clinical interaction between hard- and soft-tissue regenerative strategies, reflecting the specific conceptual focus of the review. Results: The evidence presented suggests that implant surface biofunctionalization, biologically active grafting materials, guided bone regeneration, and supplementary biological treatments may have a favorable impact on implant stability and peri-implant bone healing. Several investigations also underlined the biological dependency between peri-implant bone regeneration and soft tissue architecture, stressing the significance of soft tissue thickness, keratinized mucosa, and emergence profile stability. Even in inflammatory environments, bioactive titanium surface changes showed osteogenic potential, indicating a supporting function in early osseointegration. Conclusions: By promoting osseointegration and improving peri-implant tissue outcomes, osteo-inductive and regenerative techniques are essential to modern implant dentistry; however, their greatest potential may lie in integrated hard–soft tissue regenerative approaches aimed at improving long-term clinical predictability. To further understand the clinical efficacy of combination hard–soft tissue regeneration methods, future well-designed clinical trials with standardized outcome measures are needed. Future research should further clarify the mechanobiological principles underlying these integrated regenerative approaches. Full article
(This article belongs to the Special Issue Oral Implantology and Bone Regeneration: 2nd Edition)
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