Discovery, Modeling, Synthesis and Performance Evaluation of Enzyme Inhibitors

Dear Colleagues,

Nowadays, identifying new molecules that are both effective in vitro and in vivo is becoming a challenge.  Structure-based drug design has been facilitated by crystal structures of protein-ligand complexes. The knowledge gained from these structures can enable chemists and biologists to design new molecules with even more interesting affinities.

For this Special Issue, titled "Discovery, Modeling, Synthesis and Performance Evaluation of Enzyme Inhibitors," researchers working in this field are invited to contribute original research, short communications, or review articles related to the design of new molecules, synthesis, and evaluation of inhibitors on established or emerging targets.

This issue will be especially dedicated to research topics associated to antiproliferative/anticancer, antibacterial, and antitubercular activities. Contributions in other topics will be also considered.

Dr. Christian Lherbet
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Crystals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.