Multi-Component Hybrid and Composite Nanostructures for Healthcare Applications

A special issue of Crystals (ISSN 2073-4352).

Deadline for manuscript submissions: 25 September 2025 | Viewed by 313

Special Issue Editor


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Guest Editor
HiLASE Centre, Institute of Physics of the Czech Academy of Sciences, Za Radnicí 828, 25241 Dolni Brezany, Czech Republic
Interests: silicon nanoparticles; photoluminescence; laser ablation; biomedical applications; mid-IR lasers

Special Issue Information

Dear Colleagues,

Numerous healthcare issues, lasting from injuries and wounds to oncological and cardiovascular diseases, advance the development of novel types of medicines and drugs that can be based on inorganic/organic (nano-)structures. It requires the involvement of specific biological, chemical and physical expertise to efficiently solve such issues with minimal side effects for living organisms.

This Special Issue is focused on the synthesis and characterization of different kinds of novel organic/inorganic multi-component (nano-)structures. Recent achievements of using such kinds of (nano-)structures for different healthcare applications (e.g., biosensing, bioimaging, cancer therapy, tissue engineering, etc.) will also be presented. Potential topics of this Special Issue are devoted, but not limited, to the following:

  • Synthesis of novel organic and/or inorganic multi-component (nano-)structures;
  • Characterization of novel multi-component (nano-)structures by means of different physical and chemical techniques;
  • Study of mechanisms and processes of the interaction leading to the formation of multi-component (nano-)structures;
  • Applications of multi-component (nano-)structures for solving healthcare issues;
  • Other applications of multi-component (nano-)structures.

Original research and review papers on synthesis, characterization and healthcare applications are also welcome to be considered for publication in this Special Issue. 

Dr. Yury Ryabchikov
Guest Editor

Manuscript Submission Information

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Keywords

  • multi-component (nano-)structures
  • inorganic/organic (nano-)structures
  • synthesis and characterization
  • healthcare applications

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Published Papers (1 paper)

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Research

15 pages, 3357 KiB  
Article
Delivery Systems for Curcumin Derivatives Based on Calcium Carbonate Structures for Biomedical Applications
by Alina Raditoiu, Valentin Raditoiu, Maria Grapin, Radu Claudiu Fierascu, Cristian Andi Nicolae and Monica Florentina Raduly
Crystals 2025, 15(6), 508; https://doi.org/10.3390/cryst15060508 - 26 May 2025
Viewed by 197
Abstract
One of the most researched minerals in terms of how to produce it and the range of uses for it is calcium carbonate. This work describes how to generate hybrid materials by co-precipitating calcium carbonate loaded with either bis-dehydroxycurcumin (CCOH) or the calcium [...] Read more.
One of the most researched minerals in terms of how to produce it and the range of uses for it is calcium carbonate. This work describes how to generate hybrid materials by co-precipitating calcium carbonate loaded with either bis-dehydroxycurcumin (CCOH) or the calcium complex of bis-dehydroxycurcumin (Ca(CCOH)2). Composite materials with various morphologies were produced when calcium carbonate and different amounts of curcumin derivatives were precipitated in alcoholic media. Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and scanning electron microscopy (SEM) were used for structural and morphologic characterization of the materials, while thermal stability was verified by thermal-gravimetric analysis (TGA), and porosity analysis was performed to evaluate surfaces and pore sizes. The hybrid materials were embedded in a cosmetic matrix lacking a sun protective effect in order to assess the UV-shielding properties. The transmittance spectra were subsequently measured in the 290–400 nm region, and the sun protection factor (SPF) was calculated. Thus, the co-precipitation approach produced hybrid materials loaded with curcumin derivatives, which were further evaluated for possible applications in the medical field for the delivery of drugs or in skincare products. Full article
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