Dermatopharmaceutics: The Epitome of Skin Science

A special issue of Cosmetics (ISSN 2079-9284).

Deadline for manuscript submissions: closed (20 August 2023) | Viewed by 4515

Special Issue Editors

Dermatopharmaceutics Research Group, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, Malaysia
Interests: topical and transdermal formulations for pharmaceutical and cosmeceutical applications
Special Issues, Collections and Topics in MDPI journals
Department of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University, Kuala Lumpur, Malaysia
Interests: solid-state chemistry; particle technology; formulation engineering
Faculty of Pharmacy, International Islamic University Malaysia, Kuantan 25200, Malaysia
Interests: drug discovery involving extraction; isolation; characterization and bioactivity study of natural products from plants; wound healing; anticancer; anti-obesity and antidiabetes study of several medicinal plants using animal cell culture
Special Issues, Collections and Topics in MDPI journals
Pharmaceutics and Translational Research Group, Kulliyyah of Pharmacy, International Islamic University, Kuala Lumpur, Malaysia
Interests: nanopharmaceuticals; design of experiments; drug delivery

Special Issue Information

Dear Colleagues,

Dermatopharmaceutics concerns the overall process of developing pharmacologically active compounds into approved therapeutic formulations that are safe and effective in treating or preventing skin disorders. It is a complex process requiring inputs from various disciplines: pharmacy, chemistry, biology, medical, bioengineering, dermatology, microbiology, toxicology, statistics, and many others.  Nevertheless, the interactions between the skin and formulations remain a challenge, particularly due to the excellent barrier properties of the skin and the undesirable physicochemical properties of many active ingredients in skin formulations.

In this Special Issue, original research articles and reviews are welcome. Research areas may include, but are not limited to, the following:

  • Formulation variables affecting the development of dermatopharmaceutical products;
  • Innovative strategies to overcome the skin barrier properties for effective drug delivery;
  • Controlled-release systems for dermatopharmaceutical agents;
  • Natural products in skin formulations;
  • Drug targeting for dermal tissue;
  • Functional ingredients of dermatopharmaceutics.

It is our pleasure to invite you to submit a manuscript to this Special Issue.

Dr. Hazrina Hadi
Dr. Mohd Rushdi Abu Bakar
Prof. Dr. Muhammad Taher
Dr. Muhammad Salahuddin Haris
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cosmetics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dermatopharmaceutics
  • natural products
  • skin formulation
  • skin health
  • topical formulation
  • transdermal

Published Papers (1 paper)

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Research

14 pages, 650 KiB  
Article
Formulation of Botanical Shampoo Infused with Standardised Mangosteen Peel Extract for Healthy Hair and Scalp
Cosmetics 2023, 10(4), 109; https://doi.org/10.3390/cosmetics10040109 - 25 Jul 2023
Cited by 1 | Viewed by 3962
Abstract
In recent decades, there has been a growing demand for shampoos derived from botanical sources due to their avoidance of synthetic and highly allergenic chemicals used as bioactives and excipients. These hair care products are free from sulfates, parabens, silicones, synthetic fragrances, and [...] Read more.
In recent decades, there has been a growing demand for shampoos derived from botanical sources due to their avoidance of synthetic and highly allergenic chemicals used as bioactives and excipients. These hair care products are free from sulfates, parabens, silicones, synthetic fragrances, and artificial colours. Natural shampoos are sustainable, skin-friendly, and eco-friendly to the environment. Garcinia mangostana (Mangosteen) peel is usually discarded as agricultural waste. It consists of numerous bioactives which exhibit promising activities for hair care and scalp maintenance. This study aimed to formulate and evaluate a novel hair shampoo containing standardised mangosteen peel extract. The formulation of the mangosteen shampoo utilised botanical ingredients and naturally derived components. It underwent an evaluation to assess its physicochemical properties, including visual inspection, pH, surface tension, percentage solid content, wetting time, foam ability and stability, as well as dirt dispersion. These properties were then compared to those of two commercially available hair shampoos. Its antimicrobial activity towards Malassezia furfur ATCC 14521 and Staphylococcus aureus ATCC 25923 was also examined and compared with the commercial shampoo using the microbroth dilution method. Its antioxidant activity was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity assay. It was noticed that all formulations (F1–F4) had acceptable physicochemical properties, and they fell within the standard range. F2 had the best antifungal activity (MIC 0.039 mg/mL, MFC 0.156 mg/mL), and moderate antibacterial (MIC 2.50 mg/mL, MBC 5.00 mg/mL) and antioxidant activities (IC50 21.9 ± 3.27 mg/mL; AEAC 26.3 ± 4.06 mg AA/100 g sample). A microscopic examination of hair strands after washing revealed the successful removal of artificial sebum, signifying a good detergency effect. The physical and chemical properties of the hair shampoo formula remained stable without phase separation. In conclusion, the formulated clean hair shampoo with standardised mangosteen peel extract has good cleansing properties, and it is effective in inhibiting dandruff-causing microbial and scavenging free radicals. Full article
(This article belongs to the Special Issue Dermatopharmaceutics: The Epitome of Skin Science)
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