Recent Advances of Nanomaterials Applications in Immunomodulation and Head and Neck Oncology
A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Surface Coatings for Biomedicine and Bioengineering".
Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 358
Special Issue Editor
Special Issue Information
Dear Colleagues,
The emergence of nanotechnology-based medicine (i.e., nanomedicine), including nanoparticles, nanocarriers, and nanoprobes, is promising. Coupling nanotechnology with biology necessitates the bioengineering of functional systems in the range of fundamental macromolecules and cells, the DNA double helix (2 nm diameter), carbon–carbon bonds (0.12–0.15 nm), enzymes, and receptors.
Translational studies utilizing nanotechnology-based strategies along with active clinical trials are in progress for the diagnosis, imaging, targeting, and immunomodulation of different medical conditions. Particular interest is toward early screening, diagnosis, and targeting of tumor cells with high sensitivity and low systemic toxicity (targeted drug delivery system). Furthermore, applications of nanomaterials in immunomodulation may allow in vivo targeted cell therapy and delivery of specific immunostimulating or immunosuppressive agents. Moreover, nanoparticles, due to their unique tunable features and surface properties, can be used to explore the basic aspects of interaction between cells, immune systems, and nanomaterials at the cellular and molecular levels.
However, the current application of such technology is at an early stage of development. Further efforts toward understanding complex interactions are mandatory. Biomimetic strategies for the design of smart or functionalized nanoparticles along with the rational design of preclinical models would help to facilitate future clinical translations.
In particular, the topic of interest includes but is not limited to：
- Nanomaterials for targeting specific immune responses
- Alternative cancer immunotherapy
- Immunomodulatory nanomaterials
- Therapeutic RNA nanotechnology
- Biomimetic strategies
- Targeted drug delivery system
Dr. Ebrahimi Mehdi
Guest Editor
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