The Application of Surface-Enhanced Raman Spectroscopy (SERS) Platform

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Optical Chemical Sensors".

Deadline for manuscript submissions: 1 September 2024 | Viewed by 3470

Special Issue Editors

College of Optical and Electronic Technology, China Jiliang University, Hangzhou, China
Interests: the synthesis, characterization of noble metal nanostructures; application in surface enhanced Raman spectroscopy; SERS effect based devices
Special Issues, Collections and Topics in MDPI journals
College of Horticulture & Forestry Sciences, Huazhong Agricultural University, Wuhan, China
Interests: SERS detection of harmful substrances in food

Special Issue Information

Dear Colleagues,

Surafce-enhanced Raman spectroscopy (SERS) has been developed as a rapid spectral detection technology, which has the characteristics of high sensitivity, high accuracy, fingerprint spectrum and no interference from water molecules. With the rapid development of laser technology and the growing maturity of nano material preparation technology, SERS has been widely applied in the molecular adsorption on single crystal surface, chemical reaction mechanism, cell behavior in organism, food safety, environmental pollution, chemical weapons and artwork identification. Therefore, the topics covered in this Special Issue will involve the recent innovations in SERS platform for use in sensors, food safety and environmental applications. New detection strategy, algorithm research, SERS device and multi technology combination, as well as the synthesis and characterization of new nanomaterials for SERS sensor will be also covered in this Special Issue. Both review and original research are welcomed from the latest developments and future challenges in this exciting field of SERS detection.

Dr. Pei Liang
Dr. De Zhang
Guest Editors

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Published Papers (2 papers)

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Research

15 pages, 4455 KiB  
Article
Recyclable Multifunctional Magnetic Fe3O4@SiO2@Au Core/Shell Nanoparticles for SERS Detection of Hg (II)
by Chao Liu, Hui Wang, Shengmin Xu, Hongbao Li, Yilin Lu and Chuhong Zhu
Chemosensors 2023, 11(6), 347; https://doi.org/10.3390/chemosensors11060347 - 15 Jun 2023
Cited by 2 | Viewed by 1357
Abstract
Mercury ions can be enriched along the food chain and even low concentrations of mercury ions can seriously affect human health and the environment. Therefore, rapid, sensitive, and highly selective detection of mercury ions is of great significance. In this work, we synthesized [...] Read more.
Mercury ions can be enriched along the food chain and even low concentrations of mercury ions can seriously affect human health and the environment. Therefore, rapid, sensitive, and highly selective detection of mercury ions is of great significance. In this work, we synthesized Fe3O4@SiO2@Au three-layer core/shell nanoparticles, and then modified 4-MPy (4-mercaptopyridine) to form a SERS sensor. Mercury ions in water can be easily captured by 4-MPy which were used as the reporter molecules, and the concentration of mercury ions can be evaluated based on the spectral changes (intensification and reduction of peaks) from 4-MPy. After the mercury ion was combined with the pyridine ring, the peak intensity at 1093 cm−1 increased with the concentration of mercury ion in the range of 10 ppm–1 ppb, while the Raman intensity ratio I (416 cm−1)/I (436 cm−1) decreased with the increase of mercury ion concentration. This magnetically separatable and recyclable SERS sensor demonstrates good stability, accuracy, and anti-interference ability and shows the potential to detect actual samples. Furthermore, we demonstrate that the probe is applicable for Hg2+ imaging in macrophage cells. Full article
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14 pages, 2774 KiB  
Article
Rapid Fabrication of Homogeneous Submicron Silver Particles via a Microfluidic Chip and Use as a SERS Detection Substrate
by Junjie Chen, Suyang Li, Fuqi Yao, Wanbing Xu, Yunfeng Li, Qiang Chen and Pei Liang
Chemosensors 2023, 11(4), 232; https://doi.org/10.3390/chemosensors11040232 - 07 Apr 2023
Cited by 3 | Viewed by 1494
Abstract
Silver particles have been widely used in SERS detection as an enhancement substrate. The large-scale synthesis of Ag particles with controllable size and shape is still a challenge. We demonstrate a high-throughput method for the preparation of monodisperse submicron silver particles using S-shaped [...] Read more.
Silver particles have been widely used in SERS detection as an enhancement substrate. The large-scale synthesis of Ag particles with controllable size and shape is still a challenge. We demonstrate a high-throughput method for the preparation of monodisperse submicron silver particles using S-shaped microfluidic chips. Submicron silver particles were prepared by a simplified reduction method. By adjusting the concentration of the reducing agent ascorbic acid and the stabilizer PVP, the particle size and morphology could be controlled, obtaining a size distribution of 1–1.2 μm for flower-like silver particles and a size distribution of 0.5–0.7 μm for quasi-spherical silver particles. This microfluidic system can be used to fabricate submicron silver particles on a large scale, continuously and stably, with a production efficiency of around 1.73 mg/min. The synthesized submicron silver particles could realize ultra-sensitive SERS detection, and the lowest concentration of rhodamine 6G (R6G) that could be detected was 10−9 M. Full article
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