Biotransformation Catalyzed by Immobilized Enzyme

Dear Colleagues,

It is our pleasure to invite you to contribute to this Special Issue of Catalysts, entitled “Biotransformations Catalyzed by Immobilized Enzymes”.

Biotransformations catalyzed by immobilized enzymes represent a fascinating research and development area. From studies in the laboratory via pilot scale-up to successfully implemented large- or very large-scale production in food, pharmaceutical, biofuel, and biodegradable plastics, immobilized enzymes catalyze a broad range of reactions.

Regardless of the immobilization strategy used, the targeted advantages of immobilization are:

(i)  Easy recovery/separation of the biocatalyst from the reaction mixture;

(ii)  Easy recycling through multiple runs;

(iii)  Improved stability (and sometimes activity) versus process parameters, such as temperature or pH;

(iv) Continuous flow reactors such as packed bed reactors in order to suppress inhibition of the enzyme by the reaction product(s) while getting full conversion and pure products in cases of equimolar ratio of substrates and where appropriate process conditions are used.

Combining these four advantages, region-, chemo- or enantio-selectivity of the immobilized enzymes can lead to single successful transformation or, even better, cascade biotransformation processes.

We therefore invite you to submit your current work in this area, but also in the adjacent fields such as:

(i)  Biotransformations catalyzed by immobilized enzymes in anhydrous solvent (organic, supercritical, eutectic, ionic);

(ii)  Use and up-scalability in a reactor and/or recyclability;

(iii) Process intensification involving immobilized enzymes;

(iv) Production cost and eco-compatibility (lifecycle assessments, etc.).

In this Special Issue, we welcome contributions from all aspects of biotransformations catalyzed by immobilized enzymes. The following keywords are a guideline: enzyme immobilization, enzyme recycling, enzyme carrier interaction, continuous reactions, biocatalytic cascades, non-aqueous reaction systems, downstream processing, lifecycle assessment.

We look forward to your contributions to this interesting field.

Prof. Dr. Ulf Hanefeld
Dr. Yann P. Guiavarc'h
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.