Special Issue "Magnetic Biosensors"
A special issue of Biosensors (ISSN 2079-6374).
Deadline for manuscript submissions: 31 March 2014
Prof. Dr. Richard Luxton
Institute of Bio-Sensing Technology, University of the West of England, Bristol, Frenchay Campus, Coldharbour Lane, Bristol, BS16 1QY, UK
Interests: magneto-immunoassay; rapid diagnostics; point of care testing; environmental testing; interdisciplinary collaboration
In the growing and diversifying technologies employed to monitor biological interactions, magnetic materials have unique properties that that can be exploited for the development of biosensors for rapid measurements at the point of test. Magnetic biosensors employ paramagnetic or super-paramagnetic particles, or crystals, as a method of detecting biological interactions by measuring changes in magnetic properties or magnetically induced effects such as changes in coil inductance, resistance or magneto-optical properties. The particles used in magnetic biosensors range in size from nanometres to microns in diameter and are coated in a bio-receptor such as an antibody or strand of nucleic acid. Interaction with the target causes physical properties of the particles to change; this might be associated with mobility or size. There are a number of technologies employed to detect the particles in a magnetic biosensor including coils, GMR devices, Hall Effect devices and various optical and imaging techniques. The main advantage unique to a magnetic biosensor is the ability to accelerate the binding interactions by manipulating the paramagnetic particles in a magnetic field, allowing the particles to be moved to a sensor surface where biological interactions take place allowing rapid detection of target.
This Special Issue will be dedicated to promoting the wide range of technologies and devices that employ magnetic detection of magneto-optical effects to detect and quantitate biological targets in a sample or targets in a biological sample. Applications areas include biomedical, diagnostics, environmental analysis, food safety and biosecurity.
Prof. Dr. Richard Luxton
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 300 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- hall effect
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Type of Paper: Article
Title: Comparison of Magnetic Properties of Fe-Ni-Based Thin Film Materials with Different Dopants
Authors: Cai Liang 1,*, Chinthaka P. Gooneratne 1, QingXiao Wang 1, Yang Liu 1, Yogesh Gianchandani 2 and Jurgen Kosel 1
1 Computer, Electrical and Mathematical Sciences and Engineering, King Abdullah University of Science and Technology, 4700 Kaust, Thuwal 23955, Saudi Arabia
2 Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Michigan 48109, USA; E-Mail: firstname.lastname@example.org
Abstract: This report discusses our study of FeNi-based thin film materials with doping of Mo, Al and B using a co-sputtering process. Our findings show that FeNi doped with Mo or Al yields a magnetically soft material; doping with B further increases the softness. The out-of-plane magnetic anisotropy of FeNi thin films is reduced by doping with Al and completely removed by doping with B. The effect of doping with Mo is dependent on the dopant concentration. The coercivity of FeNiMo and FeNiAl is reduced to less than a half of that of FeNi without dopant, and a value as low as 40 A/m is obtained for FeNiB. The surfaces of the obtained FeNiMo, FeNiAl and FeNiB thin films reveal very different morphologies. The surface of FeNiMo shows nano cracks, while the one of FeNiAl films shows large clusters of FeNiAl and fewer nano cracks. When FeNi is doped with B, a very smooth morphology is developed. The crystal structure of FeNiMo strongly depends on the dopant concentration, and changes to an amorphous structure at a higher dopant level. FeNiAl thin films are polycrystalline, even at a very high dopant concentration, and FeNiB films are amorphous even at a very low dopant concentration. In addition, the magnetic properties of FeNi-based thin films are strongly dependent on the micro/nano structure of the materials in term of crystalline, cluster and morphology. FeNiB thin films are similar to the properties of the FeNiMoB thin films studied before and the Metglas 2826MB ribbons, and are a promising to replace FeNiMoB for microstructured sensors elements.
Keywords: magnetic sensor; magnetoelastic; magnetostriction; longitudinal vibration; magnetic thin films; magnetic materials
Type of Paper: Article
Title: Sensing Magnetic Directions in Birds: Radical Pair Processes Involving Cryptochrome
Authors: Roswitha Wiltschko and Wolfgang Wiltschko
Affiliations: Universität Frankfurt am Main, Germany; E-Mail: email@example.com
Abstract: Behavioral experiments revealed three characteristics of the avian magnetic compass: (1) it is an ‘inclination compass’, not based on the polarity of the magnetic field, but the axial course of the field lines, (2) it works spontaneously only in a narrow intensity window which can adapt to other intensities, and (3) it requires short-wavelength light. The Radical Pair-Model of magnetoreception can explain these properties; it is supported by experimental evidence. Cryptochrome, the suggested receptor molecule, has been found in the eyes of birds, where it is located at the disks of the outer segments of the UV-cones. By immuno-histochemical studies, we could show that it is activated by the wavelengths of light that allow magnetic compass orientation in birds.
Type of Paper: Article
Title: Asynchronous Magnetic Bead Rotation (AMBR) Microviscometer for Label-Free DNA Analysis
Author(s): Mark A. Burns * and Lavinia Li
Affiliation(s): Department of Chemical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; E-Mail: firstname.lastname@example.org
Abstract: We have developed a label-free viscosity-based DNA detection system using paramagnetic beads as an asynchronous magnetic bead rotation (AMBR) microviscometer. We have demonstrated experimentally that the bead rotation period is linearly proportional to the viscosity of a DNA solution surrounding the paramagnetic bead, as expected theoretically. Simple optical measurement of asynchronous microbead motion determines solution viscosity precisely in microscale volumes, thus allowing an estimate of DNA concentration or average fragment length. The response of the AMBR microviscometer yields reproducible measurement of DNA solutions, enzymatic digestion reaction products, and PCR reactions at template concentrations across a 5000-fold range. The results demonstrate the feasibility of viscosity-based DNA detection using AMBR in microscale aqueous volumes.
Last update: 27 November 2013