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Biosensors
Special Issues
Advanced Optics and Photonics in Biosensing Applications
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Advanced Optics and Photonics in Biosensing Applications

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Optical and Photonic Biosensors".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 463

Special Issue Editor

Prof. Dr. Hai-Feng Zhang

E-Mail Website
Guest Editor
College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology), Nanjing University of Posts and Telecommunications, Nanjing 210023, China
Interests: biosensors; photonic crystals; metamaterial; electromagnetic calculation; practical plasma technology; microwave device
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biosensors are becoming increasingly vital in fields such as diagnostics, environmental monitoring and biotechnology. The purpose of this Special Issue is to explore the latest research results and applications regarding the integration of advanced optical and photonics technologies in biosensors. By capitalizing upon the advantages of optics and photonics, such as their high sensitivity, rapid response and non-intrusion, the performance of modern biosensors has been enhanced in an unprecedented way.

This Special Issue aims to compile a series of research articles and reviews that address the implementation of advanced optical and photonics technologies in biosensors, including, but not limited to, surface plasmon resonance, photonic crystals, fiber optics, microcavity lasers, and fluorescent labeling. In addition, studies that address the whole process are welcome; this encompasses basic principles to practical applications, including the design and manufacture of novel sensors, the development of optical materials, and the characterization of optical and biological interfaces.

Through this Special Issue, readers will not only discover how optics and photonics are propelling the development of biosensor technology, but also learn how these technologies can be applied to solve practical problems. The purpose of this Special Issue is to provide a platform for researchers, engineers and clinicians to discuss the future opportunities and challenges of advanced optics and photonics in biodetection.

Prof. Dr. Hai-Feng Zhang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • photonics-based sensors
  • photonic crystal biosensors
  • optical fiber biosensors
  • metamaterial
  • metasurface
  • biomedical sensors
  • cell and tissue sensing
  • environmental monitoring
  • diagnosis
  • artificial intelligence prediction

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Published Papers (1 paper)

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Research

17 pages, 18925 KiB  
Article
Theory Design of a Virtual Polarizer with Multiscale and Multi-Biomass Sensing
by Chuanqi Wu and Haifeng Zhang
Biosensors 2025, 15(8), 516; https://doi.org/10.3390/bios15080516 - 8 Aug 2025
Abstract
Recently, more and more attention has been paid to human health with the rapid development of society. A designed virtual polarizer (VP) can realize multiscale and multi-biomass sensing, including temperature, cancerous cells, and COVID-19. Based on coherent perfect polarization conversion, a certain polarization [...] Read more.
Recently, more and more attention has been paid to human health with the rapid development of society. A designed virtual polarizer (VP) can realize multiscale and multi-biomass sensing, including temperature, cancerous cells, and COVID-19. Based on coherent perfect polarization conversion, a certain polarization conversion can be fulfilled within 1.72~2.14 THz. Then, through observing the displacement of a perfect matching point (PMP), variations in temperature can be accurately determined, covering from 299 K to 315 K, with a sensitivity (S) of 0.0198 THz/K. Moreover, a sharp coherent perfect absorption (CPA) peak generated from the VP can be employed for the detection of cancerous cells and COVID-19. The refractive index (RI) detection range of cancerous cells is from 1.36 RIU to 1.41 RIU with the sensitivity being −4.45881 THz/RIU. The average quality factor (Q), figure of merit (FOM), and detection limit (DL) are 825.36, 241.11 RIU−1, and −36.83 dB. For the COVID-19 solution concentration (SC) from 0 mM to 525 mM, by mapping SC to RI, the RI sensing range is 1.344 RIU–1.355 RIU with the S being −5.03467 THz/RIU. The relevant Q, FOM, and DL are 760.85, 244.94 RIU−1, and −36.89 dB. Based on two strategies of PMP and CPA, the proposed VP is capable of multiscale and multi-biomass sensing with excellent detection performance, providing a new detection method for biosensing. Full article
(This article belongs to the Special Issue Advanced Optics and Photonics in Biosensing Applications)
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