Gene Editing
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: closed (29 February 2016)
Special Issue Editor
Interests: CRISPR/Cas- directed gene eding; small molecules; HDR, NHEJ; regulation of genome editing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The capability of changing mammalian genes at specific sites within the chromosome has held a certain fascination for geneticists over the last 30 years. With the development of genetic tools such as single-stranded oligonucleotides, Zinc Finger Nucleases, TALENS and CRISPR/Cas9, the possibility of using genome re-engineering techniques with a high degree of precision is now a reality. But which tools, which combination of gene editing technologies, affords the greatest opportunity for success for a particular objective or application? This edition of Biomolecules, with contributions from pioneering groups as well as research groups that are leading the field, will provide answers to these important questions and will not simply be another compilation of review articles that discuss the merits of gene editing technologies. Rather, the outstanding group of authors will provide sage, experienced advice on how they choose which tools and how to utilize them to achieve the maximum benefit. Case studies with positive and negative outcomes in the decision-making process will be emphasized throughout each article, making this edition a unique yet extremely helpful addition to the gene editing literature.
Prof. Dr. Eric B. Kmiec
Guest Editor
Manuscript Submission Information
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