Epigenetics in Defying Aging and Related Diseases
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 253
Special Issue Editor
Special Issue Information
Dear Colleagues,
Aging is a natural part of life, marked by a steady decline in cell efficiency by a loosening of precise expression of genes of different metabolic pathways, which leads to morbidity and, finally, mortality. Aging is associated with a variety of human disorders, notably cancer, diabetes, cardiovascular disease, and neurological diseases. Aging not only affects the healthy human life cycle process, but it also affects other living organisms such as plants. Plant aging or senescence leads to a drastic change in plant development and growth, which causes loss of product and yield penalty. A large number of research data correlate aging to genetic and epigenetic changes. Aging is linked to substantial epigenetic modifications, which cause changes in gene expression as well as modifications in genome architecture and the epigenomic environment. Reversing these aging characteristic epigenetic alterations opens novel avenues to provide therapeutic targets for age-related diseases or to reverse aging.
This issue intends to gather research on current advancements highlighting the role of epigenetics and epigenomics in the selection and improvement of aging and associated diseases, in addition to fulfilling future health improvement objectives. Original research, reviews, and viewpoint manuscripts addressing current technical breakthroughs in epigenetics and epigenomics targeted at linking health concerns with dynamics throughout aging and associated diseases are encouraged for this Special Issue on Epigenetics in Defying Aging. Manuscripts highlighting the application of comparative histone modifications, DNA methylation, chromatin modifications, short RNAs, other new coding and non-coding RNAs, genome analysis, and transcriptomics in aging research and future challenges are also accepted. Manuscripts describing advanced bioinformatics tools and databases to strengthen the functionality of existing aging genomics and epigenomics techniques to reach a better awareness of aging and associated diseases are also invited for submission.
Dr. Niraj Lodhi
Guest Editor
Manuscript Submission Information
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Keywords
- aging
- senescence
- epigenetics
- chromatin modification
- transcriptomes
- genomics
- disease
- health improvement
- environmental stress
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