Diagnosis, Pathogenesis and Treatment of Central Nervous System Injuries

Dear Colleagues,

Injuries of the central nervous system represent a very common disease with a huge socio-economic burden. Recent epidemiological investigations have revealed that more than 50 million traumatic brain injuries (TBIs) occur yearly worldwide and are associated with an estimated annual cost of USD 400 billion. CNS injuries are very often referred to as “the most complex disease of the most complex organ”. Presently, there is room for improvement of diagnostic and prognostic tools (e.g., by the more widespread utilization or inclusion of the protein biomarkers). Moreover, practically no causal, individualized therapy exists, especially for the consequences of mild or repetitive mild TBI. One substantial reason for this is the fact that many of the pathophysiological processes that lead to long-term consequences are still unknown.

In this context, this Special Issue aims to collect experimental studies and reviews that fill the many gaps still existing in the knowledge of diagnosis, pathology and pathophysiology of CNS injuries and/or facilitate more specific and effective therapeutic interventions.

Dr. Endre Czeiter
Guest Editor

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