Special Issue "Amino Acid and Peptide Synthesis"

A special issue of Biomedicines (ISSN 2227-9059).

Deadline for manuscript submissions: 30 July 2020.

Special Issue Editors

Prof. Angelo Liguori
Website
Guest Editor
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (CS), Italy
Interests: peptide synthesis; modified amino acids; modified peptides; N-methylated amino acids; N-methylated peptides; anticancer peptides; Lewis acid mediated reactions; mass spectrometry
Special Issues and Collections in MDPI journals
Prof. Antonella Leggio
Website1 Website2
Guest Editor
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (CS), Italy
Interests: peptide synthesis; modified amino acids; modified peptides; N-methylated amino acids; N-methylated peptides; anticancer peptides; Lewis acid mediated reactions; mass spectrometry; nanostructured drug delivery systems
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue presents the latest developments in amino acid and peptide synthesis. Peptides control a wide range of physiological processes, and interact with the biological targets involved in different pathologies, thus providing a vast opportunity for biomedical applications. Recently, biologically active peptides and their therapeutic potential have aroused growing interest in the pharmaceutical industry, which has resulted in the marketing of numerous peptide drugs, many of which are in clinical trials. Peptide drugs have high specificity and selectivity, combined with low toxicity; therefore, they represent an excellent starting point for the design of new therapies. However, the biomedical application of peptide-based drugs can be restricted by their low proteolytic stability and poor bioavailability. This has led to the design and development of bioactive peptide analogs containing suitable chemical modifications that can increase their bioactivity and biodistribution.

Original research articles and review articles covering all areas of peptide synthesis, with a particular emphasis on the synthesis of modified amino acids and peptides are welcome in this Special Issue, so as to provide readers with novel insights into the synthetic strategies in this interesting research area.

This Special Issue is jointly organized between IJMS and Biomedicines. According to the aims and scopes of these journals, articles showing basic studies in biochemistry, molecular biology, and molecular medicine can be submitted to IJMS, while articles presenting a more clinical content can be submitted to Biomedicines.

Prof. Angelo Liguori
Prof. Antonella Leggio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • solid-phase peptide synthesis
  • solution-phase peptide synthesis
  • coupling agents
  • protecting groups
  • modified amino acids
  • modified peptides
  • peptidomimetics

Published Papers

This special issue is now open for submission.
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