Relationship between Insulin Resistance/Hyperinsulinemia and the Development of Atherosclerosis/Arteriosclerosis as the Cause of Cardiovascular Diseases

Dear Colleagues,

Cardiovascular diseases are the main cause of death in Western countries. Their common basis are adverse structural and functional changes within vascular walls, specifically atherosclerosis and arteriosclerosis, which tend to coexist, causing progressive, diffuse, and age-related deterioration in all vascular beds. Atherosclerosis is a chronic inflammatory and degenerative process that mainly occurs in large- and medium-sized arteries, and is morphologically characterized by asymmetric focal thickenings of the innermost layer of the artery, known as the intima. Arteriosclerosis refers to the degenerative stiffness in the arterial beds, defined as the reduced capability of an artery to expand and contract in response to pressure changes. The scope of this Special Issue is to unravel the associations between insulin resistance/hyperinsulinemia and atherosclerosis in the development of cardiovascular diseases from a molecular point of view to a population perspective.

Dr. Maria Grau
Guest Editor

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• atherosclerosis
• arteriosclerosis
• insulin resistance
• hyperinsulinemia
• cardiovascular diseases
• carotid artery diseases
• coronary artery disease
• peripheral vascular diseases