Immunomodulatory Potential of Essential Oils and Their Compounds

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Immunology and Immunotherapy".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 3948

Special Issue Editors


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Guest Editor
Department of Diagnostic Immunology, Chair of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University, 70-111 Szczecin, Poland
Interests: essential oils; essential oil compounds; Staphylococcus aureus; antibiotics; antibacterial activity; immunology of infectious diseases
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Guest Editor
Department of Pharmaceutical Microbiology and Microbiological Diagnostics, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland
Interests: microbiology; infectious diseases; multidrug resistant pathogens; secondary metabolites of plants; essential oils; antimicrobial activity

Special Issue Information

Dear Colleagues,

The use of natural chemical compounds, including essential oils (Eos) and their compounds (EOCs), to fight pathogens has been increasingly successful, and work on their implementation into treatment has accelerated significantly over the past decade. They have been used for hundreds of years as an alternative form of treatment against infections. It is worth noting that these compounds have almost no side effects, and if any occur, they are mild. Scientific advances, including the development of fields such as pharmacognosy, biochemistry, physiology, enable us to thoroughly understand the mechanism of action of phytotherapeutics.

In this Special Issue, we will publish laboratory studies and reviews on the immunostimulatory potential of essential oils and their compounds. Potential topics include in vitro/ex vivo evaluation of innate and/or acquired immune responses in the presence of (1) EOs and/or EOCs, (2) EOs or EOCs and bacterial antigens, and (3) bacteria pre-treated with EOs or EOCs.

Dr. Paweł Kwiatkowski
Dr. Monika Sienkiewicz
Guest Editors

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Keywords

  • immunomodulatory activity
  • immune response
  • immune cells
  • natural compounds
  • essential oils
  • essential oil compounds
  • cytokines
  • chemokines
  • gene expression

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Published Papers (1 paper)

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Review

34 pages, 1042 KiB  
Review
How to Naturally Support the Immune System in Inflammation—Essential Oils as Immune Boosters
by Magdalena Grazul, Paweł Kwiatkowski, Kacper Hartman, Anna Kilanowicz and Monika Sienkiewicz
Biomedicines 2023, 11(9), 2381; https://doi.org/10.3390/biomedicines11092381 - 25 Aug 2023
Cited by 9 | Viewed by 3350
Abstract
Efficient functionality of the immune system is needed to fight against the development of infectious diseases, including, among others, serious recurrent chronic infections. Research has shown that many modern common diseases, such as inflammatory bowel diseases and cardiovascular diseases, e.g., thromboembolism, cancer, obesity, [...] Read more.
Efficient functionality of the immune system is needed to fight against the development of infectious diseases, including, among others, serious recurrent chronic infections. Research has shown that many modern common diseases, such as inflammatory bowel diseases and cardiovascular diseases, e.g., thromboembolism, cancer, obesity, or depression, are connected with inflammatory processes. Therefore, new, good stimulators of the immune system’s response are sought. They include synthetic compounds as well as biological preparations such as lipopolysaccharides, enzymes, bacterial metabolites, and secondary metabolites of plants, demonstrating a multidirectional effect. Essential oils are characterized by many invaluable activities, including antimicrobial, antioxidant, anti-inflammatory, and immunostimulating. Essential oils may stimulate the immune system via the utilization of their constituents, such as antibodies, cytokines, and dendritic cells. Some essential oils may stimulate the proliferation of immune-competent cells, including polymorphonuclear leukocytes, macrophages, dendritic cells, natural killer cells, and B and T lymphocytes. This review is focused on the ability of essential oils to affect the immune system. It is also possible that essential oil components positively interact with recommended anti-inflammatory and antimicrobial drugs. Thus, there is a need to explore possible synergies between essential oils and their active ingredients for medical use. Full article
(This article belongs to the Special Issue Immunomodulatory Potential of Essential Oils and Their Compounds)
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