Alzheimer's Disease: Pathogenesis, Diagnostics and Novel Treatment Options
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: closed (30 April 2026) | Viewed by 1078
Special Issue Editors
Interests: Alzheimer's disease; neuroglia; vascular dysfunction; neuropharmacology; pharmacology; pharmacometrics; clinical pharmacology
Special Issue Information
Dear Colleagues,
For this Special Issue, we invite manuscripts focusing on Alzheimer’s disease (AD) on a variety of topics, ranging from fundamental pathophysiological mechanisms studies to clinical proof of concept and proof of mechanism studies. We encourage submissions focusing on the basic science on AD pathogenesis, including but not limited to the roles of amyloid and tau pathologies, neuroinflammation, mitochondrial dysfunction, and synaptic dysfunction. Cutting-edge research on diagnostics is welcome, such as fluid biomarkers (e.g. novel CSF and blood tests) and neuroimaging modalities. Studies leveraging AI-based diagnostics and machine learning for early identification and prognostication of AD are particularly encouraged. On the therapeutic front, we seek reports on all innovative strategies, including preclinical pharmacology or clinical studies, empirical and mechanistic modeling, as well as meta-analyses on promising disease-modifying therapies encompassing all modalities (such as small molecules, antibodies, and gene therapy).
We cordially invite authors to submit original research and review articles that focus on these important topics in AD research, aiming to foster a holistic understanding and highlight advances in diagnostics and therapies that will ultimately translate into improved outcomes for patients with AD.
Dr. Rui Zhong
Prof. Dr. Ling Li
Guest Editors
Manuscript Submission Information
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Keywords
- amyloid and tau pathology
- neuroinflammation and oxidative stress
- neuromodulation
- fluid biomarkers
- imaging and other diagnostic approaches
- small-molecule therapeutics
- novel therapeutics and emerging therapies
- disease-modifying therapies
- experimental and clinical pharmacology
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