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Audiology Research
Special Issues
A Tribute to John M. Epley
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A Tribute to John M. Epley

A special issue of Audiology Research (ISSN 2039-4349).

Deadline for manuscript submissions: 30 September 2025 | Viewed by 2596

Special Issue Editors

Dr. Giacinto Asprella Libonati

E-Mail Website
Guest Editor
Vestibology & ENT Unit, Giovanni Paolo II Hospital, 07026 Policoro, Italy
Interests: tumors; neurotology; ear; otology; human balance; hearing
Special Issues, Collections and Topics in MDPI journals
Dr. Gerard Gianoli

E-Mail Website
Guest Editor
The Ear and Balance Institute, Covington, LA, USA
Interests: vestibular disorders; vestibular testing; medical and surgical treatment of vestibular disorders
Dr. Meiho Nakayama

E-Mail Website
Guest Editor
Meiho Sleep & Balance Clinic, Nagoya, Japan
Interests: pediatric; sleep; dizziness; Meniere's disease

Special Issue Information

Dear Colleagues,

Dr. Epley was an otosurgeon and a pioneer in the cultivation of knowledge of Benign Paroxysmal Positional Vertigo—BPPV.

Dr. Epley developed the theory of canalolithiasis and laid the foundation for the nystagmus-guided approach to BPPV.

Indeed, without citing and referring to the works of Dr. Epley, no-one is able to publish about BPPV.

The purpose of this Special Issue is to promote the publication of articles on BPPV and, more broadly, on positional vertigo and the pathophysiology of the semicircular canals, taking inspiration from and recalling the works of Dr. Epley.

I invite colleagues and scientists of international repute to submit original contributions to this Special Issue, especially those who personally knew Doctor Epley.

This Special Issue of Audiology Research welcomes manuscripts comprising original work as well as review articles. The Guest Editors will be pleased to accept and review manuscripts that address the topics listed below, but papers do not need to be restricted to this list:

  • BPPV diagnosis;
  • BPPV therapy;
  • BPPV and related problems in rehabilitation;
  • Positional vertigo and positional nystagmus;
  • Residual dizziness post-maneuver in BPPV and rehabilitation;
  • Cupula pathophysiology;
  • Light/heavy cupula;
  • Vestibular rehabilitation;
  • Vestibular rehabilitation training

Dr. Giacinto Asprella Libonati
Dr. Gerard Gianoli
Dr. Meiho Nakayama
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Audiology Research is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Benign Paroxysmal Positional Vertigo—BPPV
  • positional vertigo 
  • vestibular rehabilitation

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

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Research

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27 pages, 2066 KiB  
Article
Unilateral Triple Canal Repositioning Maneuver: Principles and Design
by Marcello Cherchi
Audiol. Res. 2025, 15(3), 55; https://doi.org/10.3390/audiolres15030055 - 8 May 2025
Viewed by 289
Abstract
Background: Benign paroxysmal positional vertigo is the most common cause of dizziness over the lifespan. Management is complicated by both a diagnostic burden (correctly interpreting specific ocular motor findings) and a therapeutic burden (selecting appropriately targeted treatment maneuvers). Purpose: Devise a [...] Read more.
Background: Benign paroxysmal positional vertigo is the most common cause of dizziness over the lifespan. Management is complicated by both a diagnostic burden (correctly interpreting specific ocular motor findings) and a therapeutic burden (selecting appropriately targeted treatment maneuvers). Purpose: Devise a canalith repositioning maneuver to treat simultaneously benign paroxysmal positional vertigo affecting any combination of semicircular canals on one side. If clinically verified, then this will simplify management. Research design: After analyzing the results of a computer simulator applied to several published maneuvers for treating benign paroxysmal positional vertigo, we used basic principles to design a maneuver that simultaneously, for all three semicircular canals on one side, advances otoliths toward the crus of each canal and prevents retreat toward the ampule of each canal and then tested the maneuver in computer simulation. Study sample: Not applicable. Intervention: Not applicable. Data collection and analysis: Not applicable. Results: We developed a maneuver that computer simulation predicts will successfully treat simultaneously benign paroxysmal positional vertigo affecting any combination of semicircular canals on one side. Conclusions: This maneuver should be tested empirically as a standalone maneuver and compared to other maneuvers. Clinical relevance statement: If the efficacy of this maneuver is clinically verified, then it will simplify management by diminishing the diagnostic burden (of determining affected canals) and treatment burden (of selecting the appropriately targeted maneuvers). Full article
(This article belongs to the Special Issue A Tribute to John M. Epley)
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Review

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8 pages, 197 KiB  
Review
Epley’s Influence on Horizontal Canal BPPV Variants
by Olivia Kalmanson and Carol Foster
Audiol. Res. 2025, 15(2), 25; https://doi.org/10.3390/audiolres15020025 - 7 Mar 2025
Cited by 1 | Viewed by 694
Abstract
Dr. Epley has been instrumental in defining the mechanisms and treatment of BPPV variants, including those of the horizontal canals. Cupulolithiasis is a horizontal canal BPPV variant usually defined as direction-changing apogeotropic nystagmus. In recent years, the favored cupulolithiasis mechanism of otoconia adhering [...] Read more.
Dr. Epley has been instrumental in defining the mechanisms and treatment of BPPV variants, including those of the horizontal canals. Cupulolithiasis is a horizontal canal BPPV variant usually defined as direction-changing apogeotropic nystagmus. In recent years, the favored cupulolithiasis mechanism of otoconia adhering persistently to the cupula has been called into question. Epley was the first to propose mechanistic theories which better match the most recent evidence. From the beginning, he has demonstrated mastery over the semicircular canal pathology and otoconial mechanics. Full article
(This article belongs to the Special Issue A Tribute to John M. Epley)

Other

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6 pages, 1938 KiB  
Case Report
Inadvertent Dural Puncture Causing Low Pressure Headache and Peripheral Vestibular Bilateral Damage
by N. S. Longridge, A. I. Mallinson and R. G. Robinson
Audiol. Res. 2025, 15(2), 18; https://doi.org/10.3390/audiolres15020018 - 20 Feb 2025
Viewed by 314
Abstract
Introduction: This edition of the Audiology Research journal is dedicated to Dr. John Epley. For this reason, we would like to present a very unusual case involving the development of a bilateral abnormality of the otolith organs. The otoliths are the structures from [...] Read more.
Introduction: This edition of the Audiology Research journal is dedicated to Dr. John Epley. For this reason, we would like to present a very unusual case involving the development of a bilateral abnormality of the otolith organs. The otoliths are the structures from which calcium particles detach to induce benign paroxysmal positional vertigo, the disorder for which Dr. Epley is famous for managing. Case report: This case report outlines an unusual presentation of vestibular pathology involving the otoliths. Discussion: We suggest that the atypical presentation may be related to a bilaterally asymmetrical insult to the otoliths. Conclusions: The central insult suffered by this patient resulted in bilateral peripheral otolithic pathology. Full article
(This article belongs to the Special Issue A Tribute to John M. Epley)
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