Applications of Deep Eutectic Solvents in Life Science Engineering
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemical and Molecular Sciences".
Deadline for manuscript submissions: closed (31 October 2019) | Viewed by 3114
Special Issue Editor
Interests: chemical thermodynamics, phase equilibria, separation processes (extraction, chromatography and membranes), model-based process design
Special Issue Information
Dear Colleagues,
Increasing concerns about the environmental and health impact of some conventional solvents has turned researchers’ attention toward finding alternative green solvents. One class of promising green solvents, Deep Eutectic Solvents (DES), is usually prepared from natural, inexpensive, and biodegradable materials. DES are formed by mixing two or more components, where the resulting eutectic mixtures show a large depression in melting temperature compared to the pure compounds. As the literature shows, they have been studied extensively in recent years and show great potential in many applications, such as in separation technologies, the extraction of natural compounds, as well as the enhancement of solubility and the bioactivity of active pharmaceutical ingredients (API). However, studies investigating the applicability of these solvents at the process scale, their recycling, and their economic feasibility have yet to be published. In addition, the selection of DES candidates for a particular application is currently primarily done by trial-and-error. These important topics have not yet been covered, mainly due to lack of experimental data regarding their basic physiochemical properties, most importantly, their melting temperature.
The aim of this Special Issue is to invite experts from the fields of chemistry, (bio)chemical engineering, and pharmaceutical science in order to provide more insight into the properties and applications of DES. We are looking forward to receiving experimental and theoretical investigations concerning the structure of DES in liquid as well as solid phases, their use in the recovery and separation of (active) compounds from natural sources and synthetic liquid mixtures, their application in product formulation, and DES recycling strategies.
Prof. Mirjana Minceva
Guest Editor
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Keywords
- Deep eutectic solvents
- Natrual deep eutectic solvents
- Bioactive compounds
- Separation processes
- Extraction
- Crystallization
- Chromatography
- Drug delivery
- Solid–liquid equilibrium
- Recycling
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