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Functional Food: From Discovery to Application

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 20 August 2025 | Viewed by 3496

Special Issue Editor


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Guest Editor
Department of Food Science and Nutrition, Pukyong National University, Busan 48513, Republic of Korea
Interests: marine bioactive compounds; redox medicine; anti-obesity; molecular nutrition; bioactive compound analysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Functional foods contain a variety of beneficial components, having a positive impact on human health and well-being by targeting specific physiological functions in the body. With an unprecedented level of attention on health and well-being, the discovery and application of functional food have progressed significantly through cutting-edge technologies.

Based on this, this Special Issue intends to gather a selection of reviews and original research papers dealing with emergent and innovative applications for functional foods. Topics include, but are not limited to, the following:

  • Investigating the role of functional foods in preventing and managing chronic diseases such as cardiovascular disease, diabetes, and obesity;
  • Enhancing the bioavailability and efficacy of functional ingredients through improving food technology, formulation, or novel delivery systems;
  • Discovery of bioactive compounds and their biochemistry.

Dr. Sanggil Lee
Guest Editor

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Published Papers (1 paper)

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Review

28 pages, 686 KiB  
Review
The Impact of Sulforaphane on Sex-Specific Conditions and Hormone Balance: A Comprehensive Review
by Jed W. Fahey and Mirran Raphaely
Appl. Sci. 2025, 15(2), 522; https://doi.org/10.3390/app15020522 - 8 Jan 2025
Cited by 1 | Viewed by 3046
Abstract
The health-promoting, preventive, protective, and therapeutic applications of the natural compound sulforaphane (SF) produced from its biogenic precursor in broccoli, glucoraphanin, are extremely well established. SF has been the subject of thousands of studies and over 125 clinical trials. The many mechanisms of [...] Read more.
The health-promoting, preventive, protective, and therapeutic applications of the natural compound sulforaphane (SF) produced from its biogenic precursor in broccoli, glucoraphanin, are extremely well established. SF has been the subject of thousands of studies and over 125 clinical trials. The many mechanisms of action of SF in mammalian systems have been extensively documented. SF is the most potent naturally occurring inducer of the Keap1/Nrf2 pathway, which is most well-known for its upregulation of antioxidant and detoxification mechanisms and activation of pathways resulting in the inhibition of inflammation. Much of this regulation involves the various hormonal axes of the body. However, the influence of SF on hormone-mediated health conditions remains unexplored in recent scholarly reviews. This review aims to address this gap by exploring many of these interactions, with a focus on the health and wellness issues specific to both females and males. Full article
(This article belongs to the Special Issue Functional Food: From Discovery to Application)
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