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Advances in Artificial Intelligence for Biomedicine

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 708

Special Issue Editor


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Guest Editor
Faculty of Automation, Computers and Electronics, University of Craiova, 200440 Craiova, Romania
Interests: artificial intelligence; computer vision; software engineering; algorithm design; big data; machine learning; deep learning
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Artificial intelligence (AI) has made significant contributions to the field of biomedicine, revolutionizing biomedical research. The integration of AI in biomedicine has great promises for enhancing diagnostics, drug discovery, personalized medicine, and overall patient care. Despite its numerous benefits, there are challenges and ethical considerations regarding the application of AI in biomedicine, namely ensuring data privacy, addressing ethical concerns, maintaining the transparency and interpretability of AI algorithms, and integrating AI technologies into existing healthcare systems.

This Special Issue will aim to explore the potential of using AI technologies in biomedicine to improve diagnostics, accelerate drug discovery, enable personalized medicine, and optimize healthcare operations. Both theoretical and experimental studies are welcome, as well as comprehensive review and survey papers.

Topics of interest for this Special Issue include, but are not limited to, the following:

  • Medical imaging analysis;
  • AI for diagnosis prognosis;
  • AI for genomics and personalized medicine;
  • AI for drug discovery and development;
  • Natural Language Processing (NLP) in Electronic Health Record (EHR) analysis;
  • AI in medical robotics and surgery;
  • AI for remote patient monitoring.

Dr. Anca Udristoiu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • deep learning
  • machine learning
  • natural language processing
  • diagnosis prognosis
  • drug discovery
  • personalized medicine

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Published Papers (1 paper)

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Research

22 pages, 1429 KB  
Article
GenAI-Powered Framework for Reliable Sentiment Labeling in Drug Safety Monitoring
by Eleftherios Vouzis and Ilias Maglogiannis
Appl. Sci. 2026, 16(8), 3942; https://doi.org/10.3390/app16083942 - 18 Apr 2026
Viewed by 310
Abstract
The analysis of medical data presents an opportunity for healthcare systems to support decision-making and improve patient outcomes. In this context, the automated analysis of user-generated drug reviews offers a promising approach for monitoring medication safety, understanding patient experiences, and detecting potential adverse [...] Read more.
The analysis of medical data presents an opportunity for healthcare systems to support decision-making and improve patient outcomes. In this context, the automated analysis of user-generated drug reviews offers a promising approach for monitoring medication safety, understanding patient experiences, and detecting potential adverse effects in real time. This study advances sentiment analyses for pharmacovigilance by introducing a data-centric framework that incorporates a GenAI-powered labeling system for reliable and interpretable data annotation. A corpus of 213,869 user-generated drug reviews was processed through a hybrid labeling pipeline that reconciles user ratings, lexicon-based polarity, zero-shot transformer predictions, and GPT-5.2 as a fallback mechanism. This strategy enables the resolution of sentiment ambiguity, particularly the frequent misalignment between user-assigned ratings and underlying textual sentiment, by leveraging contextual understanding rather than relying solely on numerical scores. Drug review representations are enhanced using the Qwen3-Embedding-0.6B model, allowing improved capture of semantic nuances. Evaluated through 10-fold stratified cross-validation, the proposed labeling framework combined with a Random Forest classifier achieves a classification accuracy of 96.45%, with per-class analysis confirming consistent performance across all sentiment categories. Cross-source validation on an independent drug review dataset of 4091 reviews and a threshold sensitivity analysis further support the robustness and generalizability of the proposed approach. Full article
(This article belongs to the Special Issue Advances in Artificial Intelligence for Biomedicine)
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