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Artificial Intelligence in Medicine and Rehabilitation: Technologies and Applications: 2nd Edition

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".

Deadline for manuscript submissions: 20 July 2026 | Viewed by 628

Special Issue Editor


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Guest Editor
Department of Biomedical Engineering, Faculty of Electronics Telecommunication and Informatics, Gdansk University of Technology, 80-233 Gdansk, Poland
Interests: biomedical engineering; human system interaction; medical devices; artificial intelligence; machine learning; signal processing; computer-aided diagnosis
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Special Issue Information

Dear Colleagues,

Artificial intelligence (AI) has emerged as a transformative force in the fields of medicine and rehabilitation, offering unprecedented opportunities to enhance diagnosis, treatment, and patient care. This Special Issue aims to explore the latest advancements and applications of AI in various domains within medicine and rehabilitation.

In recent years, the rapid development of medical technologies has facilitated the collection of vast amounts of data, offering unprecedented opportunities for researchers and clinicians to leverage artificial intelligence (AI) algorithms. These advancements have ushered in a new era of medical care, where AI-driven image and signal processing techniques are revolutionizing diagnosis, treatment, and patient management. Moreover, the proliferation of wearable devices, intelligent systems, and personalized robotics has further expanded the scope of AI applications in healthcare.

This Special Issue seeks to explore the synergistic intersection of AI, medical technologies, and rehabilitation, aiming to showcase the latest developments and innovations in these interconnected domains. Researchers, clinicians, and experts are welcome to contribute original research articles, reviews, and case studies that demonstrate the impact of AI in medicine and rehabilitation.

Dr. Tomasz Kocejko
Guest Editor

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Keywords

  • artificial intelligence
  • machine learning
  • deep learning
  • computer vision
  • image processing
  • image analysis
  • signal processing
  • signal analysis
  • computer-aided diagnosis
  • human–computer interface and interaction
  • human–machine interface and interaction
  • personalized robotics
  • translational medicine
  • intelligent systems

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Published Papers (1 paper)

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Research

24 pages, 1441 KB  
Article
Unsupervised Detection of Pathological Gait Patterns via Instantaneous Center of Rotation Analysis
by Ludwin Molina Arias and Magdalena Smoleń
Appl. Sci. 2026, 16(8), 3976; https://doi.org/10.3390/app16083976 - 19 Apr 2026
Viewed by 304
Abstract
This study introduces a novel unsupervised framework, ICR-LLS, for detecting pathological gait patterns using instantaneous center of rotation (ICR) trajectories of the shank in the sagittal plane. ICR trajectories were computed from two-dimensional kinematic data captured at the lateral femoral epicondyle and lateral [...] Read more.
This study introduces a novel unsupervised framework, ICR-LLS, for detecting pathological gait patterns using instantaneous center of rotation (ICR) trajectories of the shank in the sagittal plane. ICR trajectories were computed from two-dimensional kinematic data captured at the lateral femoral epicondyle and lateral malleolus for both shanks, producing four-dimensional multivariate time series for each gait trial. Pairwise trajectory dissimilarities were quantified using circularly aligned Dynamic Time Warping (DTW), preserving temporal and spatial structure. The resulting dissimilarity matrix was embedded into a three-dimensional space using a force-directed network layout, enabling intuitive visualization of inter-subject gait relationships. Density-based clustering (DBSCAN), enhanced with a consensus-based ensemble approach, was employed to automatically identify clusters representing typical (healthy) gait patterns and outliers corresponding to pathological deviations. The framework is evaluated on a public dataset comprising individuals with Parkinson’s disease (PD) and healthy controls, achieving a normalized mutual information (NMI) of 0.449 and a Separation-to-Compactness Ratio (SCR) of 6.754, indicating a meaningful cluster structure. In addition, classification-oriented metrics yield an accuracy of 90%, sensitivity of 70%, and specificity of 96.7%, supporting the method’s effectiveness in distinguishing pathological gait. By combining minimal 2D kinematic inputs with unsupervised learning, ICR-LLS provides an interpretable framework for the exploratory analysis of gait variability, and although further validation is required, the findings suggest that ICR trajectories may serve as a meaningful biomechanical descriptor for characterizing pathological locomotion. Full article
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