Special Issue "Pathogen–Host Interaction by Borrelia burgdorferi"
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: closed (31 October 2020) | Viewed by 24265
Interests: Lyme disease; spirochetes; infection; biofilm; persisters; antibiotic resistance; connection of cancer to bacterial infections
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Special Issue in Antibiotics: Novel Therapeutic Approches for Lyme Disease
Borrelia burgdorferi senso lato (s.l.), the etiological agent of Lyme disease, is well known to disseminate to and colonize various organisms and tissues of its natural reservoir hosts, which are crucial steps for its pathogenicity and overall survival. To invade and persist in the different tissues, B. burgdorferi s.l. has developed several very sophisticated strategies, including manipulating innate and adaptive immune systems, binding to host proteins to initiate vascular and extracellular matrix interactions, and even highjacking and stimulating host proteases to digest and remodel healthy tissues. Furthermore, intracellular localization of B. burgdorferi s.l. is also reported for different eukaryotic cells that can further help to evade the immune system and other environmental stress factors.
A clear understanding of the exact mechanism of host dissemination and invasion by B. burgdorferi s.l could help us develop therapeutic targets for chronic conditions such as Lyme carditis, arthritis, and neuroborreliosis.
This Special Issue seeks manuscript submissions that further our understanding of B. burgdorferi s.l. host dissemination and tissue invasion though original research articles, short communications, reviews, case reports, and perspectives.
Prof. Dr. Eva Sapi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Lyme disease
- antibiotic resistance
- pathogen-host interaction