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Novel Targets of Drug Monitoring for Antibiotics

Special Issue Information

Dear Colleagues,

Drug monitoring is crucial to successfully curing patients’ infections, as typified by vancomycin. Just over 20 years ago, target concentration intervention (TCI) was distinguished from therapeutic drug monitoring (TDM). Both TCI and TDM can be considered as approaches to centration-controlled dosing of individual patients (Holford, 1999). Therapeutic drug monitoring (TDM) is a branch of clinical chemistry and clinical pharmacology that specializes in the measurement of medication concentrations in blood. On the other hand, target concentration intervention (TCI) embraces pharmacokinetic and pharmacodynamic concepts and uses the idea of a target effect and associated target concentration to make rational individual dose decisions. This Special Issue aims to publish high-quality manuscripts evaluating the novel target of drug monitoring for antibiotics. In the era of individualized medicine, further research of the safety and efficacy of drug monitoring of antibiotics based on novel targets (e.g., unbound drug concentration, metabolites and/or biomarkers) is warranted.

Dr. Yasuhiro Tsuji
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • therapeutic drug monitoring
  • target concentration intervention
  • individual dose
  • antibiotics
  • dose adjustment

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Antibiotics - ISSN 2079-6382