Interaction of Pathogenic Escherichia coli with the Host: Pathogenomics, Virulence and Antibiotic Resistance
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: closed (20 March 2023) | Viewed by 235
Special Issue Editor
Special Issue Information
Dear Colleagues，
Over the last 25 years, there has been an increasing prevalence of multidrug resistance and extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae detected amongst both community and hospital patients. Rates of resistance are particularly high in healthcare settings as a result of cross-transmission, poor infection control strategies and the increasing use of and consumption of antimicrobial agents. Antimicrobial agents are progressively losing efficacy in treating bacterial infections due to the seemingly unstoppable rise in antimicrobial resistance (AMR).
Due to its ubiquity in the gastrointestinal tract, E. coli is often used as a sentinel to measure antimicrobial resistance. There has been a sharp global increase in the global prevalence in the frequency of Escherichia coli (E. coli) infections caused by multi-drug-resistant strains and this is associated with excess morbidity, mortality, longer hospital stays and higher healthcare costs.
Interventions to support a reduction in infections caused by E. coli are very much needed, though insufficient data in many areas of the world regarding prevalence can make this difficult. Therefore, the main subjects of this Special Issue will include the epidemiology and surveillance of AMR, approaches to improve the inappropriate use of antimicrobials and strategies to curb the emergence, maintenance and transmission of resistance genes between hosts and surveillance studies.
Dr. Steven Kemp
Guest Editor
Manuscript Submission Information
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Keywords
- antimicrobial resistance
- bacterial transmission
- pathogenesis
- infectious disease
- E. coli
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