Pathophysiology, Diagnosis and Therapy of Sepsis
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotic Therapy in Infectious Diseases".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 2477
Special Issue Editors
Interests: sepsis; immunity; multidrug resistant microorganisms; intensive care; shock
Interests: infection; intensive care; sepsis; anti-infective agents
Special Issues, Collections and Topics in MDPI journals
Interests: intensive care; sepsis; septic shock
Interests: emergency medicine; critical care medicine; ICU; sepsis; mechanical ventilation; pharmacodynamics; airway management; cardiopulmonary resuscitation; hemodynamics; anesthesiology
Special Issue Information
Dear Colleagues,
Sepsis is a clinical syndrome that results from the dysregulated inflammatory response to infection that leads to organ dysfunction. The resulting losses to society in terms of financial burden, morbidity, and mortality are enormous.
Comprehensively defining "sepsis" has been the subject of constant development and refinement over the last decades. Although our understanding of sepsis origin, pathophysiology, and immunological mechanisms have progressed over the last three decades, our options for specific and successful therapeutic interventions remain limited. Only timely fluid resuscitation and early administration of broad-spectrum antibiotics have been shown to reduce mortality. A decisive factor is the time of correct diagnosis and the initiation of causal, supportive, and adjunctive measures. Moreover, the high heterogeneity of host response to infections and its changes with time require a personalized approach to patient management.
This Special Issue focuses on manuscripts related to the recent advancements in the knowledge of sepsis mechanisms, diagnostic protocols including new biomarkers, and new developing therapies for improving the prognosis of septic patients.
Dr. Massimo Girardis
Dr. Marc Leone
Dr. Anne-Claire Lukaszewicz
Dr. Gennaro De Pascale
Guest Editors
Manuscript Submission Information
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