Special Issue "The Antimicrobial or Antitumor Activities of Essential Oils"
Deadline for manuscript submissions: closed (30 November 2020).
Interests: pharmacology; chemotherapy; multidrug resistance; natural products; pharmacognosy and phytotherapy
Drug therapy plays a crucial role in the treatment of pathogen infections, as well as in the control of human cancer. However the success of the therapy is threatened by the increasing prevalence of drug resistance, innate or acquired and above all in its multiple form (multidrug resistance, MDR). MDR is multifactorial, and pleiotropic cellular signals are simultaneously involved in this process. The multiplicity of the drug resistance determinants raises the question about the optimal strategies to deal with them. In the necessity to find new therapeutic strategies, plant secondary metabolites including essential oils (EOs), may represent one of the best sources. EOs in plants act as constitutive defenses against biotic and abiotic stress. The biological properties of EOs are widely documented from a vast literature that demonstrates theirs in vitro anticancer, anti-bioceptive, antiviral, antiphlogistic and antimicrobial activity. EOs represent the most important sources of drugs used in pharmaceutical therapies due to their low toxicity, good pharmacokinetic and multitarget activity. Moreover, essential oils contain several chemical classes of compounds whose heterogeneity of active moieties can help prevent the development of drug resistance. This special issue focuses on the possible useful antimicrobial or antitumor activities of essential oils or their constituents against pathogen infections or neoplastic disease. Of particular interest will also be studies on models characterized also by drug resistance, which underline the role of EO as possible modulators of resistance to multiple drugs or as a source of promising lead compounds.
Dr. Manuela Labbozzetta
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Essential oils (EOs)
- Pathogen infections
- Antitumor and Antimicrobial Activities
- Multidrug resistance modulators